Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.31 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.31 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5724916 | 1.00 | CHRM2 (0.32) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL5727812 | 0.92 | HTR2A (0.37) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL8790520 | 0.85 | TBXA2R (0.33) | — | |
| SCHEMBL5725514 | 0.85 | TBXA2R (0.33) | — | |
| SCHEMBL5725511 | 0.85 | TBXA2R (0.33) | — | |
| SCHEMBL5724914 | 0.80 | SCN5A (0.35) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL5724872 | 0.75 | HTR2A (0.40) | — | |
| SCHEMBL7979790 | 0.74 | CHRM3 (0.45) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL7979788 | 0.74 | CHRM3 (0.45) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| Bromide SCHEMBL7977250 | 0.73 | CHRM3 (0.44) | CHRM2CHRM4CHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0812318-A1 | 4-AMINOTETRAHYDROBENZISOXAZOLE OR -ISOTHIAZOLE COMPOUNDS | H. LUNDBECK A/S (DK) | 1997-12-17 | — | — | EP | disclosed |
| WO-1996026929-A1 | 4-AMINOTETRAHYDROBENZISOXAZOLE OR -ISOTHIAZOLE COMPOUNDS | H. LUNDBECK A/S (DK) | 1996-09-06 | — | — | WO | disclosed |