Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | CFTR | P13569 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MYC | P01106 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17010932 | 0.88 | SLC6A3 (0.54) | SLC6A3SLC6A4SLC6A2LMNATSHR | |
| SCHEMBL30284984 | 0.84 | HPGD (0.51) | SLC6A3SLC6A4SLC6A2LMNATSHR | |
| SCHEMBL12712110 | 0.83 | CYP46A1 (0.45) | LMNAALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL25450956 | 0.81 | SLC6A3 (0.48) | SLC6A3SLC6A4SLC6A2LMNATSHR | |
| SCHEMBL12712112 | 0.81 | CYP46A1 (0.43) | LMNAALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL12712127 | 0.81 | CYP46A1 (0.43) | LMNAALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL14080168 | 0.80 | SLC6A3 (0.47) | SLC6A3SLC6A4SLC6A2LMNATSHR | |
| SCHEMBL24800447 | 0.80 | BCAT2 (0.50) | LMNATSHRALDH1A1HSD17B10KDM4E | |
| SCHEMBL8791050 | 0.79 | SLC6A3 (0.48) | SLC6A3SLC6A4SLC6A2LMNATSHR | |
| SCHEMBL69464 | 0.78 | SLC6A3 (0.67) | SLC6A3SLC6A4SLC6A2LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230064360-A1 | HETEROCYCLES AND USES THEREOF | KUMQUAT BIOSCIENCES INC. | 2023-03-02 | — | — | US | disclosed |
| EP-0652869-B1 | IMIDAZOLE ETHERS HAVING A II ANTAGONIST ACTIVITY | LUSO FARMACO INST (IT) | 1997-03-26 | — | — | EP | disclosed |
| US-5538987-A | Imidazole ethers having a II antagonist activity | ISTITUTO LUSO FARMACO D'ITALIA S.P.A. (IT) | 1996-07-23 | — | — | US | disclosed |
| EP-0652869-A1 | IMIDAZOLE ETHERS HAVING A II ANTAGONIST ACTIVITY. | LUSO FARMACO INST (IT) | 1995-05-17 | — | — | EP | disclosed |
| WO-1994002467-A1 | IMIDAZOLE ETHERS HAVING A II ANTAGONIST ACTIVITY | INSTITUTO LUSO FARMACO D'ITALIA S.P.A. (IT) | 1994-02-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230064360-A1 | HETEROCYCLES AND USES THEREOF | KRAS, HRAS, TP53 | SLC6A3 3535/4885SLC6A4 3920/4885SLC6A2 4126/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.