Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.51 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.51 |
| ▸ | GMNN | O75496 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9174480 | 0.88 | RAB9A (0.60) | RAB9ACYP1A2SMN1; SMN2CHRM2LMNA | |
| SCHEMBL8790717 | 0.82 | RAB9A (0.53) | RAB9ACYP1A2SMN1; SMN2CHRM2LMNA | |
| SCHEMBL8790761 | 0.80 | TTR (0.50) | ALDH1A1 | |
| SCHEMBL7852676 | 0.79 | CHEK1 (0.54) | LMNAALDH1A1 | |
| SCHEMBL9596507 | 0.78 | RAB9A (0.61) | RAB9ACYP1A2CHRM2LMNAUSP2 | |
| SCHEMBL1364796 | 0.78 | ALDH1A1 (0.62) | RAB9ACYP1A2SMN1; SMN2CHRM2LMNA | |
| SCHEMBL5937266 | 0.78 | ALDH1A1 (0.66) | RAB9ACYP1A2SMN1; SMN2ALDH1A1 | |
| SCHEMBL9369774 | 0.76 | RAB9A (0.59) | RAB9ACYP1A2CHRM2LMNAUSP2 | |
| SCHEMBL11750738 | 0.76 | RAB9A (0.44) | RAB9ACYP1A2SMN1; SMN2CHRM2LMNA | |
| SCHEMBL4541695 | 0.75 | RAB9A (0.72) | RAB9ACYP1A2CHRM2LMNAUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0393604-B1 | 6,11-Dihydro-5H-pyrido(2,3-b)(1,5,)benzodiazepin-5-ones and thiones and their use in the prevention or treatment of AIDS | BOEHRINGER INGELHEIM PHARMA (US) | 1997-12-29 | — | — | EP | disclosed |
| US-5571809-A | The treatment of HIV-1 infection using certain pyridodiazepines | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1996-11-05 | — | — | US | disclosed |
| EP-0393604-A2 | 6,11-Dihydro-5H-pyrido(2,3-b)(1,5,)benzodiazepin-5-ones and thiones and their use in the prevention or treatment of AIDS | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 1990-10-24 | — | — | EP | disclosed |