SCHEMBL879092

SCHEMBL879092

c1ccc2c(c1)CNCO2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
OXTR P30559 1/20 1.00
GAA P10253 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
MAOB P27338 2/20 0.41
PNMT P11086 1/20 0.41
CD44 P16070 1/20 0.41
RYR2 Q92736 1/20 0.39
MAOA P21397 1/20 0.39
ABCG2 Q9UNQ0 1/20 0.39
ITGB2 P05107 1/20 0.39
ICAM1 P05362 1/20 0.39
ITGAL P20701 1/20 0.39
HTR2C P28335 1/20 0.36
KMT2A Q03164 1/20 0.35
LMNA P02545 1/20 0.34
CRHBP P24387 1/20 0.34
HTT P42858 1/20 0.34
CRHR2 Q13324 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17969084 1.00 OXTR (1.00) OXTRGAANPSR1MAOBPNMT
SCHEMBL29356240 1.00 OXTR (1.00) OXTRGAANPSR1MAOBPNMT
SCHEMBL27711072 0.94 OXTR (0.88) OXTRGAANPSR1MAOBPNMT
Piperidine SCHEMBL8139417 0.89 OXTR (0.79) OXTRGAANPSR1MAOBPNMT
Acetone SCHEMBL28394022 0.89 OXTR (0.79) OXTRGAANPSR1MAOBPNMT
SCHEMBL4503860 0.80 OXTR (0.67) OXTRGAANPSR1MAOBPNMT
SCHEMBL29580106 0.80 OXTR (0.67) OXTRGAANPSR1MAOBPNMT
SCHEMBL27702505 0.79 OXTR (0.63) OXTRHTR2CLMNA
SCHEMBL400964 0.78 OXTR (0.64) OXTRGAANPSR1MAOBPNMT
SCHEMBL4493830 0.78 OXTR (0.64) OXTRMAOBPNMTCD44MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 355 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4259610-B1 CATALYSTS FOR BENZOXAZINE LUXEMBOURG INST SCIENCE & TECH LIST (LU) 2024-09-18 EP claimed
CN-116583516-A Catalyst for benzoxazines 卢森堡科学技术研究院 2023-08-11 CN claimed
US-20220185802-A1 BENZOXAZINE MONOMERS AND POLYMERIC COATINGS UNIVERSITY OF MANCHESTER (GB) 2022-06-16 US claimed
CN-113795489-A Benzoxazine monomers and polymer coatings 卢森堡科学技术研究院 2021-12-14 CN claimed
CN-111100291-B Preparation method of polybenzoxazine-reinforced three-dimensional graphene foam 中国科学院上海硅酸盐研究所 2021-08-31 CN claimed
EP-2938652-B1 POLYMERIZABLE COMPOSITION INCLUDING A BENZOXAZINE AND AN ACID-FORMING PEROXIDE CATALYST, ARTICLE, AND METHOD 3M INNOVATIVE PROPERTIES CO (US) 2021-03-31 EP claimed
CN-111100291-A Preparation method of polybenzoxazine-reinforced three-dimensional graphene foam 中国科学院上海硅酸盐研究所 2020-05-05 CN claimed
US-9371477-B2 Polymerizable composition including a benzoxazine and an acid-forming peroxide catalyst, article, and method 3M INNOVATIVE PROPERTIES COMPANY (US) 2016-06-21 US claimed
US-20150299541-A1 POLYMERIZABLE COMPOSITION INCLUDING A BENZOXAZINE AND AN ACID-FORMING PEROXIDE CATALYST, ARTICLE, AND METHOD 3M INNOVATIVE PROPERTIES COMPANY (US) 2015-10-22 US claimed
US-9145354-B2 Pharmaceutical compounds ASTEX THERAPEUTICS LIMITED (GB) 2015-09-29 US claimed
CN-1057728-C Method of producing laminate HITACHI CHEMICAL CO LTD (JP) 2000-10-25 CN claimed
EP-0566018-B1 Benzoxazinone and benzothiazinone derivatives endowed with cardiovascular activity ITALFARMACO SPA (IT) 1998-08-05 EP claimed
CN-1119583-A Method of producing laminate HITACHI CHEMICAL CO LTD (JP) 1996-04-03 CN claimed
EP-0356379-B1 Resins curable into fire-retardant and heat-resistant plastic materials, and method for their preparation GURIT ESSEX AG (CH) 1996-03-20 EP claimed
EP-0356379-A1 Resins curable into fire-retardant and heat-resistant plastic materials, and method for their preparation Gurit-Essex AG (CH) 1990-02-28 EP claimed
US-RE32745-E Polymeric resins derived from 1-oxa-3-aza tetraline group-containing compounds and cycloaliphatic epoxides GURIT-ESSEX AG (CH) 1988-09-06 US claimed
EP-0147382-B1 PROCESS FOR DEPOSITION OF RESIN DISPERSIONS ON METAL SUBSTRATES Monsanto Company (US) 1988-05-11 EP claimed
EP-0178414-B1 CHEMICALLY CURABLE RESINS DERIVED FROM 1-OXA-3-AZA-TETRALIN GROUPS CONTAINING COMPOUNDS AND CYCLOALIPHATIC EPOXY RESINS, PROCESS FOR THEIR PREPARATION AND CURE AS WELL AS THE USE OF SUCH RESINS Gurit-Essex AG (CH) 1988-01-13 EP claimed
US-4607091-A Polymeric resins derived from 1-oxa-3-aza tetraline group-containing compounds and cycloaliphatic epoxides GURIT-ESSEX AG (CH) 1986-08-19 US claimed
EP-0178414-A1 Chemically curable resins derived from 1-oxa-3-aza-tetralin groups containing compounds and cycloaliphatic epoxy resins, process for their preparation and cure as well as the use of such resins Gurit-Essex AG (CH) 1986-04-23 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220185802-A1 BENZOXAZINE MONOMERS AND POLYMERIC COATINGS DDO, DAO, AOC1 OXTR 4110/4885GAA 2953/4885NPSR1 1329/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.