Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | SMYD3 | Q9H7B4 | 10/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8790644 | 0.84 | SMYD3 (0.39) | SMYD3MEN1KMT2A | |
| SCHEMBL2319139 | 0.81 | GAA (0.41) | GAAMAPTMEN1KMT2ANOS3 | |
| SCHEMBL8790345 | 0.80 | SMN1; SMN2 (0.47) | SMYD3DPP4CYP2C19 | |
| SCHEMBL2862448 | 0.80 | GAA (0.45) | GAAMAPTKDM4EMEN1KMT2A | |
| SCHEMBL8791961 | 0.79 | CYP2D6 (0.41) | SMYD3MEN1KMT2ADPP4DPP8 | |
| SCHEMBL18979956 | 0.77 | GAA (0.37) | GAAMAPT | |
| SCHEMBL19995830 | 0.77 | HPGD (0.48) | GAAMAPTKDM4EMEN1KMT2A | |
| SCHEMBL7139016 | 0.77 | MAPT (0.63) | GAAMAPTKDM4EMEN1KMT2A | |
| SCHEMBL25553449 | 0.76 | SMN1; SMN2 (0.43) | GAAMAPTKDM4E | |
| SCHEMBL28429967 | 0.75 | GAA (0.43) | GAAMAPTMEN1KMT2ANOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0800516-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS HAVING SUBSTITUTED (b)-AMINO ACID RESIDUES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | NIPPON STEEL CORPORATION (JP) | 1997-10-15 | — | — | EP | disclosed |