Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 4/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.45 |
| ▸ | CCR1 | P32246 | 1/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16370709 | 0.81 | ALDH1A1 (0.51) | SMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL8790971 | 0.80 | GAA (0.40) | CYP2C19DPP4SMYD3 | |
| SCHEMBL31397369 | 0.79 | SMN1; SMN2 (0.60) | SMN1; SMN2NPC1RAB9ACYP2C19HTT | |
| SCHEMBL7363296 | 0.79 | SMN1; SMN2 (0.48) | SMN1; SMN2NPC1RAB9ACYP2C19DPP4 | |
| SCHEMBL7363294 | 0.79 | SMN1; SMN2 (0.48) | SMN1; SMN2NPC1RAB9ACYP2C19DPP4 | |
| SCHEMBL16466450 | 0.78 | MEN1 (0.58) | SMN1; SMN2NPC1RAB9ACYP2C19DPP4 | |
| SCHEMBL20612426 | 0.78 | MEN1 (0.58) | SMN1; SMN2NPC1RAB9ACYP2C19DPP4 | |
| SCHEMBL16465286 | 0.78 | MEN1 (0.58) | SMN1; SMN2NPC1RAB9ACYP2C19DPP4 | |
| SCHEMBL8790644 | 0.76 | SMYD3 (0.39) | KCNH2SMYD3 | |
| SCHEMBL15106080 | 0.76 | ALDH1A1 (0.43) | SMN1; SMN2NPC1RAB9ACYP2C19DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0800516-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS HAVING SUBSTITUTED (b)-AMINO ACID RESIDUES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | NIPPON STEEL CORPORATION (JP) | 1997-10-15 | — | — | EP | disclosed |