Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.54 |
| ▸ | RAB9A | P51151 | 8/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | TP53 | P04637 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29531707 | 0.77 | NPC1 (0.69) | NPC1RAB9AMAPTPSMB8SMN1; SMN2 | |
| SCHEMBL824375 | 0.77 | NPC1 (0.69) | NPC1RAB9AMAPTPSMB8SMN1; SMN2 | |
| SCHEMBL57537 | 0.76 | NPC1 (0.54) | NPC1RAB9AMAPTPSMB8SMN1; SMN2 | |
| SCHEMBL20663406 | 0.76 | NQO2 (0.43) | NPC1RAB9AMAPTSMN1; SMN2LMNA | |
| Iodomethane SCHEMBL4457728 | 0.73 | ELANE (0.54) | NPC1RAB9AMAPTSMN1; SMN2TP53 | |
| SCHEMBL6445384 | 0.71 | NPC1 (0.54) | NPC1RAB9AMAPTPSMB8SMN1; SMN2 | |
| SCHEMBL129661 | 0.71 | MAPT (0.59) | NPC1RAB9AMAPTPSMB8SMN1; SMN2 | |
| SCHEMBL10045305 | 0.71 | NPC1 (0.54) | NPC1RAB9AMAPTPSMB8SMN1; SMN2 | |
| SCHEMBL22190326 | 0.71 | NPC1 (0.54) | NPC1RAB9AMAPTPSMB8SMN1; SMN2 | |
| SCHEMBL9542349 | 0.71 | NPC1 (0.54) | NPC1RAB9AMAPTPSMB8SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106715428-A | Pesticidally active tetracyclic derivatives with sulphur containing substituents | 先正达参股股份有限公司 | 2017-05-24 | — | — | CN | claimed |
| CN-1220057-C | Method for identification and enumeration of biological cells and reagents therefor | ABX SA (FR) | 2005-09-21 | — | — | CN | claimed |
| CN-1385701-A | Methods and reagents for identification and enumeration of biological cells | ABX SA (FR) | 2002-12-18 | — | — | CN | claimed |
| US-20250333399-A1 | INHIBITORS OF FIBROBLAST GROWTH FACTOR RECEPTOR KINASES | KHORA SPV 1 LLC (US) | 2025-10-30 | — | — | US | disclosed |
| US-12331039-B2 | Inhibitors of fibroblast growth factor receptor kinases | KHORA SPV 1, LLC (US) | 2025-06-17 | — | — | US | disclosed |
| US-20230384671-A1 | LAMINATE OF NEGATIVE TONE LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF PREPARING NEGATIVE TONE LITHOGRAPHIC PRINTING PLATE | FUJIFILM CORPORATION (JP) | 2023-11-30 | — | — | US | disclosed |
| US-11818932-B2 | Organic light-emitting device | SAMSUNG DISPLAY CO., LTD. (KR) | 2023-11-14 | — | — | US | disclosed |
| US-11795163-B2 | Compound for inhibiting nicotinamide phosphoribosyltransferase and composition containing same | CHECKMATE THERAPEUTICS INC. | 2023-10-24 | — | — | US | disclosed |
| US-20230312481-A1 | SUBSTITUTED (PHTHALAZIN-1-YLMETHYL)UREAS, SUBSTITUTED N-(PHTHALAZIN-1-YLMETHYL)AMIDES, AND ANALOGUES THEREOF | ARBUTUS BIOPHARMA CORP (CA) | 2023-10-05 | — | — | US | disclosed |
| EP-4234539-A1 | ORGANIC MATERIAL FOR AN ELECTRONIC OPTOELECTRONIC DEVICE AND ELECTRONIC DEVICE COMPRISING THE ORGANIC MATERIAL | Novaled GmbH (DE) | 2023-08-30 | — | — | EP | disclosed |
| WO-2023136457-A1 | NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME | 주식회사 엘지화학 | 2023-07-20 | — | — | WO | disclosed |
| CN-100475855-C | Arylsulfinate salts in initiator systems for polymeric reactions | 3M INNOVATIVE PROPERTIES CO (US) | 2009-04-08 | — | — | CN | disclosed |
| CN-101394830-A | Cosmetic agents comprising purine and/or purine derivatives I | HENKEL KGAA (DE) | 2009-03-25 | — | — | CN | disclosed |
| WO-2007062342-A1 | HETEROCYCLIC CETP INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-05-31 | — | — | WO | disclosed |
| CN-1882307-A | Method for dyeing fibres containing keratine | HENKEL KGAA (DE) | 2006-12-20 | — | — | CN | disclosed |
| CN-1220057-C | Method for identification and enumeration of biological cells and reagents therefor | ABX SA (FR) | 2005-09-21 | — | — | CN | disclosed |
| CN-1385701-A | Methods and reagents for identification and enumeration of biological cells | ABX SA (FR) | 2002-12-18 | — | — | CN | disclosed |
| EP-0584817-B1 | Process for the preparation of a grain stabilized high chloride tabular grain photographic emulsion (II) | EASTMAN KODAK CO (US) | 1996-04-10 | — | — | EP | disclosed |
| US-5298387-A | Displacing adsorbed 2-hydroaminoazine with 5-iodobenzoxazolium compound | EASTMAN KODAK COMPANY (US) | 1994-03-29 | — | — | US | disclosed |
| EP-0584817-A1 | Process for the preparation of a grain stabilized high chloride tabular grain photographic emulsion (II) | EASTMAN KODAK COMPANY (US) | 1994-03-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12331039-B2 | Inhibitors of fibroblast growth factor receptor kinases | FGFR1, FGFR2, FGFR3 | NPC1 1043/4885RAB9A 2047/4885MAPT 3513/4885 |
| US-20250333399-A1 | INHIBITORS OF FIBROBLAST GROWTH FACTOR RECEPTOR KINASES | FGFR1, FGFR2, FGFR3 | NPC1 1043/4885RAB9A 2047/4885MAPT 3513/4885 |
| US-20230312481-A1 | SUBSTITUTED (PHTHALAZIN-1-YLMETHYL)UREAS, SUBSTITUTED N-(PHTHALAZIN-1-YLMETHYL)AMIDES, AND ANALOGUES THEREOF | NSD3, PML, NSD1 | NPC1 910/4885RAB9A 2543/4885MAPT 484/4885 |
| US-11795163-B2 | Compound for inhibiting nicotinamide phosphoribosyltransferase and composition containing same | NAMPT, NAPRT, NNT | NPC1 269/4885RAB9A 2946/4885MAPT 182/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.