Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1000643 | 0.83 | ALDH1A1 (0.57) | ALDH1A1MAPTKMT2AMEN1TSHR | |
| SCHEMBL11326711 | 0.77 | ALDH1A1 (0.46) | ALDH1A1MAPTKMT2AMEN1TSHR | |
| SCHEMBL8791877 | 0.77 | ALDH1A1 (0.44) | ALDH1A1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL11337541 | 0.76 | ALDH1A1 (0.46) | ALDH1A1MAPTKMT2AMEN1TSHR | |
| SCHEMBL11342787 | 0.76 | ALDH1A1 (0.46) | ALDH1A1MAPTKMT2AMEN1TSHR | |
| SCHEMBL11337543 | 0.76 | ALDH1A1 (0.46) | ALDH1A1MAPTKMT2AMEN1TSHR | |
| SCHEMBL7275956 | 0.75 | TSHR (0.42) | ALDH1A1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL11328052 | 0.74 | ALDH1A1 (0.44) | ALDH1A1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL11337831 | 0.73 | TSHR (0.50) | ALDH1A1MAPTKMT2AMEN1GAA | |
| SCHEMBL526873 | 0.73 | ALDH1A1 (0.68) | ALDH1A1MAPTKMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0770686-A1 | Process for the production of thiols | SOCIETE DES PRODUITS NESTLE S.A. (CH) | 1997-05-02 | — | — | EP | disclosed |