Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1000643 | 0.80 | ALDH1A1 (0.57) | TSHRKMT2AHSD17B10HPGDUSP2 | |
| SCHEMBL11326711 | 0.77 | ALDH1A1 (0.46) | TSHRKMT2AHSD17B10HPGDUSP2 | |
| SCHEMBL25263678 | 0.77 | CES2 (0.61) | TSHRKMT2AHSD17B10HPGDCES2 | |
| SCHEMBL11328052 | 0.75 | ALDH1A1 (0.44) | TSHRKMT2AHSD17B10HPGDUSP2 | |
| SCHEMBL11337834 | 0.75 | MAOB (0.51) | TSHRKMT2AHSD17B10HPGDCES2 | |
| SCHEMBL179961 | 0.75 | ALDH1A1 (0.64) | TSHRKMT2AHSD17B10HPGDHTT | |
| SCHEMBL11337541 | 0.74 | ALDH1A1 (0.46) | TSHRKMT2AHSD17B10HPGDUSP2 | |
| SCHEMBL11337543 | 0.74 | ALDH1A1 (0.46) | TSHRKMT2AHSD17B10HPGDUSP2 | |
| SCHEMBL11342787 | 0.74 | ALDH1A1 (0.46) | TSHRKMT2AHSD17B10HPGDUSP2 | |
| SCHEMBL8791885 | 0.73 | ALDH1A1 (0.45) | TSHRKMT2AHSD17B10HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4303689-A | Flavoring with pyrazine derivatives | FIRMENICH SA (CH) | 1981-12-01 | — | — | US | disclosed |