Hydrazine

Hydrazine

SCHEMBL8791966

NN.O=S(=O)(O)Oc1ccccc1Cl

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
SLC22A6 Q4U2R8 1/20 0.43
FABP1 P07148 1/20 0.41
CYP1A2 P05177 1/20 0.40
GAA P10253 1/20 0.40
CYP2C19 P33261 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
PKM P14618 1/20 0.39
CXCL8 P10145 1/20 0.39
NFE2L2 Q16236 1/20 0.38
HPGD P15428 3/20 0.38
XIAP P98170 1/20 0.38
PTGS2 P35354 1/20 0.38
HDAC6 Q9UBN7 1/20 0.37
ELANE P08246 1/20 0.37
KDM4E B2RXH2 2/20 0.37
ALDH1A1 P00352 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5728043 0.96 SLC22A6 (0.46) LMNASMN1; SMN2SLC22A6FABP1CYP1A2
SCHEMBL30616021 0.96 SLC22A6 (0.46) LMNASMN1; SMN2SLC22A6FABP1CYP1A2
SCHEMBL514247 0.80 SLC22A6 (0.53) LMNASMN1; SMN2SLC22A6FABP1NFE2L2
SCHEMBL31243101 0.80 FABP1 (0.41) SMN1; SMN2SLC22A6FABP1CYP1A2GAA
SCHEMBL1955905 0.80 FABP1 (0.41) SMN1; SMN2SLC22A6FABP1CYP1A2GAA
SCHEMBL3375397 0.79 CA2 (0.50) LMNASMN1; SMN2NFE2L2HPGDPTGS2
Ammonia Solution, Strong SCHEMBL1278643 0.78 SLC22A6 (0.52) LMNASMN1; SMN2SLC22A6FABP1NFE2L2
SCHEMBL1882763 0.78 SLC22A6 (0.52) LMNASMN1; SMN2SLC22A6FABP1ELANE
SCHEMBL28288293 0.78 SLC22A6 (0.52) LMNASMN1; SMN2SLC22A6FABP1NFE2L2
SCHEMBL28479379 0.77 ELANE (0.61) LMNASMN1; SMN2CYP1A2GAACYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104151188-A Preparation method of 2-chlorophenylhydrazine sulfate TIANJIN CHEM REAGENT RES INST 2014-11-19 CN claimed
CN-106565534-B A kind of synthetic method of aryl hydrazine sulfate 浙江奇彩环境科技股份有限公司 2018-10-30 CN disclosed
CN-107663161-A A kind of continuous stream synthesis technique of phenylhydrazine salt and substituted benzene hydrazonium salt 上海惠和化德生物科技有限公司 2018-02-06 CN disclosed
CN-106565534-A Synthesis method for aromatic hydrazine sulfate 浙江奇彩环境科技股份有限公司 2017-04-19 CN disclosed
CN-104151188-A Preparation method of 2-chlorophenylhydrazine sulfate TIANJIN CHEM REAGENT RES INST 2014-11-19 CN disclosed
EP-0485636-B1 INDOLE DERIVATIVE TORAY INDUSTRIES (JP) 1997-03-12 EP disclosed
EP-0735026-A1 Method for the production of isoquinoline derivatives and their use as intermediates in the preparation of indole derivatives TORAY INDUSTRIES, INC. (JP) 1996-10-02 EP disclosed
US-5539119-A MULTISTAGE FORMATION BY OXIDATION, REDUCING A CARBAMATE TO FORM AN ENAMINE, FORMING AN OXIDE TORAY INDUSTRIES, INC. (JP) 1996-07-23 US disclosed
US-5244904-A Immunorepressant, analgesic TORAY INDUSTRIES, INC. (JP) 1993-09-14 US disclosed
EP-0485636-A1 INDOLE DERIVATIVE TORAY INDUSTRIES, INC. (JP) 1992-05-20 EP disclosed