Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | AGT | P01019 | 2/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8791377 | 0.86 | AGTR1 (0.40) | AGTR1AGTR2KMT2AAGTPTGS2 | |
| SCHEMBL796 | 0.85 | AGTR1 (0.50) | AGTR1AGTR2AGT | |
| SCHEMBL29404889 | 0.85 | AGTR1 (0.50) | AGTR1AGTR2AGT | |
| SCHEMBL7196989 | 0.83 | AGTR1 (0.41) | AGTR1AGTR2PTGS2 | |
| SCHEMBL7384556 | 0.82 | AGTR1 (0.42) | AGTR1AGTR2AGT | |
| SCHEMBL9587058 | 0.82 | AGTR1 (0.40) | AGTR1AGTR2AGT | |
| SCHEMBL8791472 | 0.78 | AGTR1 (0.40) | AGTR1AGTR2AGT | |
| SCHEMBL9033026 | 0.78 | AGTR1 (0.38) | AGTR1PTGS1PTGS2 | |
| SCHEMBL10299418 | 0.77 | POLB (0.39) | AGTR1AGTR2KMT2A | |
| SCHEMBL29931185 | 0.77 | AGTR1 (0.44) | AGTR1AGTR2AGT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0652869-B1 | IMIDAZOLE ETHERS HAVING A II ANTAGONIST ACTIVITY | LUSO FARMACO INST (IT) | 1997-03-26 | — | — | EP | disclosed |
| US-5538987-A | Imidazole ethers having a II antagonist activity | ISTITUTO LUSO FARMACO D'ITALIA S.P.A. (IT) | 1996-07-23 | — | — | US | disclosed |
| EP-0652869-A1 | IMIDAZOLE ETHERS HAVING A II ANTAGONIST ACTIVITY. | LUSO FARMACO INST (IT) | 1995-05-17 | — | — | EP | disclosed |
| WO-1994002467-A1 | IMIDAZOLE ETHERS HAVING A II ANTAGONIST ACTIVITY | INSTITUTO LUSO FARMACO D'ITALIA S.P.A. (IT) | 1994-02-03 | — | — | WO | disclosed |