Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | PLAU | P00749 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30071572 | 1.00 | ALDH1A1 (0.53) | ALDH1A1POLBPLAUHDAC6HDAC8 | |
| SCHEMBL613262 | 0.85 | KDM4E (0.62) | PLAUHDAC6HDAC8HDAC2KDM4E | |
| SCHEMBL4161973 | 0.82 | MEN1 (0.61) | ALDH1A1POLBHDAC6HDAC8HDAC2 | |
| SCHEMBL29582662 | 0.82 | PLAU (0.53) | ALDH1A1PLAUHDAC6HDAC8HDAC2 | |
| SCHEMBL940919 | 0.82 | PLAU (0.53) | ALDH1A1PLAUHDAC6HDAC8HDAC2 | |
| SCHEMBL12200767 | 0.81 | ALDH1A1 (0.49) | ALDH1A1POLBHDAC6KDM4EHPGD | |
| SCHEMBL3111273 | 0.81 | KDM4E (0.54) | ALDH1A1POLBHDAC6HDAC8KDM4E | |
| SCHEMBL16147608 | 0.81 | POLB (0.45) | ALDH1A1POLBHDAC6KDM4ESMN1; SMN2 | |
| SCHEMBL2662442 | 0.79 | HSP90AA1 (0.53) | ALDH1A1PLAUHDAC6HDAC8HDAC2 | |
| SCHEMBL8918916 | 0.79 | NPC1 (0.54) | ALDH1A1POLBHDAC6HDAC8HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101870824-B | Method for preparing azo colouring agent by utilizing supergravity reactor | UNIV BEIJING CHEMICAL | 2013-05-01 | — | — | CN | claimed |
| CN-101870824-A | Method for preparing azo colouring agent by utilizing supergravity reactor | UNIV BEIJING CHEMICAL | 2010-10-27 | — | — | CN | claimed |
| US-6548647-B2 | Spraying coupling components in solution or suspension to collide in reactor chamber, then pressurizing to remove; useful for offset printing inks | CLARIANT GMBH (DE) | 2003-04-15 | — | — | US | claimed |
| US-20020055619-A1 | Process for preparing azo colorants | CLARIANT GMBH | 2002-05-09 | — | — | US | claimed |
| EP-1195411-A1 | Process for the preparation of azo colourants | Clariant GmbH (DE) | 2002-04-10 | — | — | EP | claimed |
| EP-4605392-A1 | METHODS FOR TREATING CANCER | Antares Therapeutics, Inc. (US) | 2025-08-27 | — | — | EP | disclosed |
| WO-2024086809-A1 | METHODS FOR TREATING CANCER | SCORPION THERAPEUTICS, INC. (US) | 2024-04-25 | — | — | WO | disclosed |
| US-11957683-B2 | Bicyclic compounds | ALIGOS THERAPEUTICS, INC. (US) | 2024-04-16 | — | — | US | disclosed |
| US-11952374-B2 | Bicyclic compounds | ALIGOS THERAPEUTICS, INC. (US) | 2024-04-09 | — | — | US | disclosed |
| CN-116724038-A | Bicyclic compounds | 安力高医药股份有限公司 | 2023-09-08 | — | — | CN | disclosed |
| EP-4232450-A1 | BICYCLIC COMPOUNDS | Aligos Therapeutics, Inc. (US) | 2023-08-30 | — | — | EP | disclosed |
| CN-111601807-B | Exo-azaspiro inhibitors of MENIN-MLL interactions | 詹森药业有限公司 | 2023-03-31 | — | — | CN | disclosed |
| CN-1398282-A | Method for producing azo colorants in microreactors | CLARIANT INT LTD (CH) | 2003-02-19 | — | — | CN | disclosed |
| EP-1257602-A1 | METHOD FOR PRODUCTION OF AZO DYES IN MICROREACTORS | CLARIANT INTERNATIONAL LTD. (CH) | 2002-11-20 | — | — | EP | disclosed |
| US-6469147-B2 | DIAZOTIZATION | CLARIANT FINANCE (BVI) LIMITED (VG) | 2002-10-22 | — | — | US | disclosed |
| US-20020055619-A1 | Process for preparing azo colorants | CLARIANT GMBH | 2002-05-09 | — | — | US | disclosed |
| EP-1195411-A1 | Process for the preparation of azo colourants | Clariant GmbH (DE) | 2002-04-10 | — | — | EP | disclosed |
| US-20010029294-A1 | Preparation of azo colorants in microreactors | CLARIANT INTERNATIONAL LTD. | 2001-10-11 | — | — | US | disclosed |
| WO-2001059013-A1 | METHOD FOR PRODUCTION OF AZO DYES IN MICROREACTORS | CLARIANT INTERNATIONAL LTD (CH) | 2001-08-16 | — | — | WO | disclosed |
| US-4031073-A | Monoazo pigments containing barbituric acid or thio- or imino-derivatives thereof | CIBA-GEIGY CORPORATION (US) | 1977-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11952374-B2 | Bicyclic compounds | SLC10A1, PKD1, CYP11B2 | ALDH1A1 543/4885POLB 3123/4885PLAU 2569/4885 |
| US-11957683-B2 | Bicyclic compounds | SLC10A1, PKD1, CYP11B2 | ALDH1A1 543/4885POLB 3123/4885PLAU 2569/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.