Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 12/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | CHUK | O15111 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.37 |
| ▸ | MYC | P01106 | 1/20 | 0.37 |
| ▸ | WDR5 | P61964 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8788632 | 0.83 | PTGS2 (0.39) | PTGS2IKBKBCHUKPTGS1 | |
| SCHEMBL8789881 | 0.77 | MYC (0.50) | MYCWDR5 | |
| SCHEMBL8789362 | 0.77 | ERBB2 (0.40) | MYCWDR5 | |
| SCHEMBL8790492 | 0.74 | MYC (0.53) | MYCWDR5 | |
| SCHEMBL19450642 | 0.72 | PTGS2 (0.43) | PTGS2PTGS1 | |
| SCHEMBL19434380 | 0.72 | PTGS2 (0.46) | PTGS2PTGS1 | |
| SCHEMBL15221164 | 0.69 | CA2 (0.66) | PTGS2 | |
| SCHEMBL8789377 | 0.68 | IDO1 (0.42) | — | |
| SCHEMBL27659883 | 0.65 | CHUK (0.53) | PTGS2IKBKBCHUKPTGS1 | |
| SCHEMBL16979041 | 0.64 | IKBKB (0.49) | PTGS2IKBKBCHUKPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799216-A1 | SUBSTITUTED THIADIAZOLES, COMPOSITIONS CONTAINING THEM AND THEIR USE AS ANTIMICROBIAL AND MARINE ANTIFOULING AGENTS | THE DOW CHEMICAL COMPANY (US) | 1997-10-08 | — | — | EP | disclosed |
| WO-1996019467-A1 | SUBSTITUTED THIADIAZOLES, COMPOSITIONS CONTAINING THEM AND THEIR USE AS ANTIMICROBIAL AND MARINE ANTIFOULING AGENTS | THE DOW CHEMICAL COMPANY (US) | 1996-06-27 | — | — | WO | disclosed |
| US-5488060-A | Substituted thiadiazoles, compositions containing them and their use as antimicrobial and marine antifouling agents | THE DOW CHEMICAL COMPANY (US) | 1996-01-30 | — | — | US | disclosed |