Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VNN1 | O95497 | 7/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | GPR52 | Q9Y2T5 | 2/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | LTC4S | Q16873 | 2/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL690788 | 0.87 | VNN1 (0.55) | VNN1KMT2AHDAC3HDAC1HDAC2 | |
| SCHEMBL842061 | 0.84 | VNN1 (0.49) | VNN1LTC4S | |
| SCHEMBL27757817 | 0.75 | CES2 (0.56) | VNN1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL24851858 | 0.72 | VNN1 (0.46) | VNN1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL758527 | 0.71 | VNN1 (0.59) | VNN1CNR2CES2 | |
| SCHEMBL1182880 | 0.71 | VNN1 (0.51) | VNN1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL1183537 | 0.69 | VNN1 (0.47) | VNN1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL18286288 | 0.69 | VNN1 (1.00) | VNN1 | |
| SCHEMBL20185799 | 0.68 | VNN1 (1.00) | VNN1 | |
| SCHEMBL842548 | 0.68 | CETP (0.41) | VNN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1951690-B1 | HETEROCYCLIC CETP INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2012-03-28 | — | — | EP | disclosed |