Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8587501 | 1.00 | MEN1 (0.43) | MEN1KMT2ASLC6A3CHRNB4CHRNA3 | |
| SCHEMBL8587502 | 1.00 | MEN1 (0.43) | MEN1KMT2ASLC6A3CHRNB4CHRNA3 | |
| SCHEMBL8792376 | 0.96 | MEN1 (0.48) | MEN1KMT2ASLC6A3SLC6A2SLC6A4 | |
| SCHEMBL521429 | 0.84 | SLC6A3 (0.41) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL4366937 | 0.81 | HTR2A (0.39) | MEN1KMT2ASLC6A3SLC6A2SLC6A4 | |
| SCHEMBL8706824 | 0.80 | MEN1 (0.50) | MEN1KMT2ASLC6A3CHRNB4CHRNA3 | |
| SCHEMBL8706820 | 0.80 | MEN1 (0.50) | MEN1KMT2ASLC6A3CHRNB4CHRNA3 | |
| SCHEMBL8791343 | 0.80 | ALOX15 (0.41) | SLC6A3SLC6A2SLC6A4MAPK1 | |
| SCHEMBL8792123 | 0.79 | SMN1; SMN2 (0.47) | MEN1KMT2ASLC6A3SLC6A2SLC6A4 | |
| SCHEMBL8792127 | 0.79 | SMN1; SMN2 (0.47) | MEN1KMT2ASLC6A3SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758330-A1 | BIPHENYLCARBOXAMIDES USEFUL AS 5-HT1D ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1997-02-19 | — | — | EP | disclosed |
| WO-1995030675-A1 | BIPHENYLCARBOXAMIDES USEFUL AS 5-HT1D ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-11-16 | — | — | WO | disclosed |