Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 8/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28772030 | 0.88 | ALDH1A1 (0.53) | POLBMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL14228573 | 0.86 | ALDH1A1 (0.55) | POLBMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL8319530 | 0.84 | MAPT (0.47) | POLBMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL9982871 | 0.84 | KMT2A (0.43) | POLBMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL8798225 | 0.79 | TSHR (0.48) | POLBMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL10144751 | 0.79 | L3MBTL1 (0.66) | POLBMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL1643994 | 0.78 | NPSR1 (0.68) | POLBMEN1KMT2AMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL28316912 | 0.77 | MAPT (0.42) | POLBMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL27885280 | 0.77 | MAPT (0.44) | POLBMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL12069190 | 0.76 | CKS1B (0.45) | LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0444944-B1 | Synthesis and elucidation of azamitosene and iminoazamitosene | RES CORP TECHNOLOGIES INC (US) | 1997-09-24 | — | — | EP | disclosed |
| US-5246955-A | Pyrrolo(1,2-a)benzimidazole 5,8-diones, antitumor | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1993-09-21 | — | — | US | disclosed |
| EP-0449649-A2 | Antineoplastic quinones and methods of using same | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1991-10-02 | — | — | EP | disclosed |
| EP-0444944-A2 | Synthesis and elucidation of azamitosene and iminoazamitosene | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1991-09-04 | — | — | EP | disclosed |
| US-5015742-A | Antitumor agents | ARIZONA BOARD OF REGENTS (US) | 1991-05-14 | — | — | US | disclosed |