SCHEMBL8793301

SCHEMBL8793301

OCc1ccc(SSc2ccc(CO)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.48
PRSS1 P07477 1/20 0.42
PRSS2 P07478 1/20 0.42
PRSS3 P35030 1/20 0.42
VHL P40337 1/20 0.41
ELOC Q15369 1/20 0.41
ELOB Q15370 1/20 0.41
LTA4H P09960 1/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA4 P22748 1/20 0.41
CA6 P23280 1/20 0.41
CA5A P35218 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41
CA14 Q9ULX7 1/20 0.41
CA5B Q9Y2D0 1/20 0.41
DAO P14920 1/20 0.39
DDB1 Q16531 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18364906 0.88 MAPT (0.45) TSHRMAPTSMN1; SMN2NOS3NOS1
SCHEMBL18364910 0.88 ALDH1A1 (0.44) TSHRPRSS1PRSS2PRSS3VHL
SCHEMBL12589778 0.82 APP (0.47) LTA4HCA12CA1CA2CA7
SCHEMBL10887327 0.82 TSHR (0.48) TSHRPRSS1PRSS2PRSS3VHL
SCHEMBL41775 0.80 TSHR (0.67) TSHRPRSS1PRSS2PRSS3VHL
SCHEMBL16710812 0.79 PPARG (0.38) TSHRPRSS1PRSS2PRSS3VHL
SCHEMBL21297145 0.78 MKNK1 (0.56) TSHRMKNK1MKNK2MEN1KMT2A
SCHEMBL564610 0.78 SLC6A4 (0.52) TSHRMAPTMEN1KMT2ACYP3A4
SCHEMBL2393902 0.78 TSHR (0.43) TSHRPRSS1PRSS2PRSS3VHL
SCHEMBL21886058 0.78 PRSS1 (0.44) TSHRPRSS1PRSS2PRSS3VHL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119875490-A Ti (titanium)3C2Tx@NiFe2O4Preparation method of self-repairing noise-reducing anti-corrosion coating 中国海洋大学 2025-04-25 CN claimed
CN-119842307-A Two-dimensional porous nano NiFe2O4Preparation method of self-repairing noise-reducing anti-corrosion coating 中国海洋大学 2025-04-18 CN claimed
CN-116218345-B Preparation method and application of photo-thermal nano heterojunction and self-repairing anticorrosive paint thereof 中国海洋大学 2024-04-26 CN claimed
CN-116218345-A Preparation method and application of photo-thermal nano heterojunction and self-repairing anticorrosive paint thereof 中国海洋大学 2023-06-06 CN claimed
US-5342724-A Preparing polyester from diol and diacid wherein one of the monomers has disulfuide linkage, reacting polyester with unsaturated monomer to create addition polymer blocks linked by sulfide group from dislufide linkage EASTMAN KODAK COMPANY (US) 1994-08-30 US claimed
CN-119875490-A Ti (titanium)3C2Tx@NiFe2O4Preparation method of self-repairing noise-reducing anti-corrosion coating 中国海洋大学 2025-04-25 CN disclosed
CN-119842307-A Two-dimensional porous nano NiFe2O4Preparation method of self-repairing noise-reducing anti-corrosion coating 中国海洋大学 2025-04-18 CN disclosed
CN-118755253-A High-resilience shoe midsole material and forming method thereof 浙江红蜻蜓鞋业股份有限公司 2024-10-11 CN disclosed
CN-116218345-B Preparation method and application of photo-thermal nano heterojunction and self-repairing anticorrosive paint thereof 中国海洋大学 2024-04-26 CN disclosed
CN-116218345-A Preparation method and application of photo-thermal nano heterojunction and self-repairing anticorrosive paint thereof 中国海洋大学 2023-06-06 CN disclosed
EP-0552553-B1 Sulfonimidamides as antineoplastic agents LILLY CO ELI (US) 1997-07-23 EP disclosed
US-5342724-A Preparing polyester from diol and diacid wherein one of the monomers has disulfuide linkage, reacting polyester with unsaturated monomer to create addition polymer blocks linked by sulfide group from dislufide linkage EASTMAN KODAK COMPANY (US) 1994-08-30 US disclosed
EP-0236880-B1 Penem derivatives ERBA CARLO SPA (IT) 1994-07-20 EP disclosed
US-5258406-A Antitumor agents ELI LILLY AND COMPANY (US) 1993-11-02 US disclosed
EP-0552553-A1 Sulfonimidamides as antineoplastic agents ELI LILLY AND COMPANY (US) 1993-07-28 EP disclosed
US-4886793-A PENICILLINS; HUMANS OR ANIMALS FARMITALIA CARLO ERBA, S.R.L. (IT) 1989-12-12 US disclosed
EP-0236880-A2 Penem derivatives FARMITALIA CARLO ERBA S.r.l. (IT) 1987-09-16 EP disclosed
US-4027090-A SYNERGISTIC MOLECULAR WEIGHT CONTROL STANDARD OIL COMPANY (US) 1977-05-31 US disclosed