SCHEMBL564610

SCHEMBL564610

CSc1ccc(CO)cc1

nearest known ligand 0.52

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 13/20 0.52
HTT P42858 1/20 0.50
MAOA P21397 1/20 0.50
SLC6A2 P23975 1/20 0.50
SLC6A3 Q01959 1/20 0.50
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
CYP1A2 P05177 1/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45
NPC1 O15118 1/20 0.44
MAPT P10636 1/20 0.44
RAB9A P51151 1/20 0.44
TSHR P16473 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7786897 0.87 ALDH1A1 (0.46) SLC6A4HTTMAOASLC6A2SLC6A3
SCHEMBL9474042 0.87 LTA4H (0.59) SLC6A4HTTMAOASLC6A2SLC6A3
SCHEMBL31727451 0.85 TSHR (0.40) SLC6A4HTTMAOASLC6A2SLC6A3
SCHEMBL8653103 0.81 PTGS2 (0.58) SLC6A4HTTMAOASLC6A2SLC6A3
SCHEMBL1097266 0.80 CA2 (0.52) SLC6A4HTTMAOASLC6A2SLC6A3
SCHEMBL10887327 0.78 TSHR (0.48) SLC6A4CYP3A4NPC1MAPTRAB9A
SCHEMBL8793301 0.78 TSHR (0.48) MEN1KMT2ACYP3A4MAPTTSHR
SCHEMBL13026656 0.78 SLC6A4 (0.56) SLC6A4MAOASLC6A2SLC6A3MEN1
SCHEMBL81913 0.77 SLC6A4 (0.51) SLC6A4HTTMAOASLC6A2SLC6A3
SCHEMBL83839 0.76 ALDH1A1 (0.58) SLC6A4MAOASLC6A2SLC6A3MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 527 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025053791-A1 ONE-POT GRAFTING OF POLYMERS FROM ALCOHOLS AND BIOMASSES NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2025-03-13 WO claimed
CN-116283831-B P-nitrobenzene derivative and preparation method and application thereof 中国医学科学院医药生物技术研究所 2024-07-23 CN claimed
WO-2023027630-A9 A FLOW REACTOR, METHODS OF FABRICATION AND REACTIONS THEREOF NATIONAL UNIVERSITY OF SINGAPORE (SG) 2023-07-27 WO claimed
WO-2023027630-A2 A FLOW REACTOR, METHODS OF FABRICATION AND REACTIONS THEREOF NATIONAL UNIVERSITY OF SINGAPORE (SG) 2023-03-02 WO claimed
CN-113784953-A Heterocyclyl (phenyl) carbinol compounds useful for treating hyperglycemia 阿托基公司 2021-12-10 CN claimed
EP-1300487-B1 Copper plating bath ROHM & HAAS ELECT MAT (US) 2017-10-04 EP claimed
US-9309274-B2 Redox-active structures and devices utilizing the same YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2016-04-12 US claimed
US-20150007371-A1 REDOX-ACTIVE STRUCTURES AND DEVICES UTILIZING THE SAME YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2015-01-01 US claimed
US-8865890-B2 Redox-active structures and devices utilizing the same YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) 2014-10-21 US claimed
US-20140196180-A1 REDOX-ACTIVE STRUCTURES AND DEVICES UTILIZING THE SAME YEDA RESEARCH & DEVELOPMENT COMPANY LTD. (IL) 2014-07-10 US claimed
US-6773573-B2 ELECTROLYTIC CELLS; BATH MIXTURE CONTAINING ALCOHOLS; STABILITY SHIPLEY COMPANY, L.L.C. 2004-08-10 US claimed
EP-1198455-B1 PROCESS FOR PREPARING 1-(6-METHYLPYRIDIN-3-YL)-2- (4-(METHYLSULPHONYL) PHENYL] ETHANONE LONZA AG (CH) 2003-12-10 EP claimed
US-20030102226-A1 Plating bath and method for depositing a metal layer on a substrate SHIPLEY COMPANY, L.L.C. 2003-06-05 US claimed
US-6566527-B1 Five-step process; starting with p-(methylthio)benzyl alcohol, chlorination, cyaniding, condensation with 6-methylnicotinic ester, hydrolysis and decarboxylation, and oxidation MERCK & CO., INC. 2003-05-20 US claimed
US-20030088107-A1 Process for preparing 1-(6-methylpyridin-3-yl)-2-[4-(methylsulfonyl)phenyl]ethanone BESSARD YVES (CH) 2003-05-08 US claimed
EP-1300487-A1 Plating bath and method for depositing a metal layer on a substrate Shipley Co. L.L.C. (US) 2003-04-09 EP claimed
EP-1198455-A1 PROCESS FOR PREPARING 1-(6-METHYLPYRIDIN-3-YL)-2- (4-(METHYLSULPHONYL) PHENYL] ETHANONE Lonza AG (CH) 2002-04-24 EP claimed
WO-2001007410-A1 PROCESS FOR PREPARING 1-(6-METHYLPYRIDIN-3-YL)-2-[(4-(METHYLSULPHONYL) PHENYL] ETHANONE LONZA AG (CH) 2001-02-01 WO claimed
US-5344928-A Phenothiazine compounds for cancer treatment or immunoassay using chemiluminescence TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1994-09-06 US claimed
EP-0510668-A2 Phenothiazine derivatives, their production and use TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1992-10-28 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030088107-A1 Process for preparing 1-(6-methylpyridin-3-yl)-2-[4-(methylsulfonyl)phenyl]ethanone PTGES2, PTGS1, CYP2J2 SLC6A4 4580/4885HTT 4502/4885MAOA 2232/4885
US-20140196180-A1 REDOX-ACTIVE STRUCTURES AND DEVICES UTILIZING THE SAME GPX4, GPX1, LPO SLC6A4 4004/4885HTT 4470/4885MAOA 83/4885
US-20150007371-A1 REDOX-ACTIVE STRUCTURES AND DEVICES UTILIZING THE SAME GPX4, GPX1, LPO SLC6A4 4004/4885HTT 4470/4885MAOA 83/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.