Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | HPGD | P15428 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | MPO | P05164 | 2/20 | 0.54 |
| ▸ | QPCT | Q16769 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8794286 | 0.96 | ALDH1A1 (0.57) | ALDH1A1HPGDKDM4EMAPK1HSD17B10 | |
| SCHEMBL8614885 | 0.81 | MAPK1 (0.47) | ALDH1A1HPGDMAPK1HSD17B10SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8619108 | 0.80 | MAPK1 (0.46) | ALDH1A1HPGDMAPK1HSD17B10SMN1; SMN2 | |
| SCHEMBL8795336 | 0.79 | ALDH1A1 (0.56) | ALDH1A1HPGDKDM4EMAPK1HSD17B10 | |
| SCHEMBL8616729 | 0.78 | CYP1A2 (0.37) | ALDH1A1HPGDKDM4EQPCTCYP1A2 | |
| SCHEMBL30159317 | 0.78 | SMN1; SMN2 (0.63) | ALDH1A1HPGDKDM4EMAPK1HSD17B10 | |
| SCHEMBL8793396 | 0.78 | BACE1 (0.47) | CYP1A2MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL8619504 | 0.78 | CYP1A2 (0.36) | ALDH1A1HPGDKDM4EQPCTCYP1A2 | |
| SCHEMBL8614516 | 0.77 | MAPK1 (0.43) | ALDH1A1HPGDMAPK1HSD17B10SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8794370 | 0.77 | BACE1 (0.46) | CYP1A2MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0612729-B1 | Pyridine derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-04-23 | — | — | EP | disclosed |
| US-5561147-A | ANTIINFLAMMATORY AGENT, ANTIPYRETIC, ANALGESICS, ANTIALLERGENS, IMMUNOSUPPRESSANTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-10-01 | — | — | US | disclosed |
| US-5457106-A | Antiinflammatory agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-10-10 | — | — | US | disclosed |
| US-5389658-A | Administering as antipyretic, antiinflammatory, analgesic, antiallergic, or immunosupressive agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-02-14 | — | — | US | disclosed |
| EP-0612729-A2 | Pyridine derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1994-08-31 | — | — | EP | disclosed |
| US-5246948-A | Antiinflammatory, antipyretic, analgesic, antiallergic, immunosupressing or immunomodulating activity | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-09-21 | — | — | US | disclosed |
| EP-0522606-A2 | Pyridine derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-01-13 | — | — | EP | disclosed |