Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICMT | O60725 | 3/20 | 0.40 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10129837 | 0.76 | GPR88 (0.46) | CYP19A1GPR88GAAIDO1 | |
| SCHEMBL23573913 | 0.76 | CYP19A1 (0.36) | CYP19A1TSHRGPR88IDO1 | |
| SCHEMBL19535067 | 0.75 | CYP19A1 (0.46) | DPP4CYP19A1HRH4HRH3MIF | |
| SCHEMBL3737019 | 0.75 | ICMT (0.47) | ICMTDPP4HPGDTSHRHSD17B10 | |
| SCHEMBL10129843 | 0.74 | GPR88 (0.44) | DPP4CYP19A1GPR88TP53IDO1 | |
| SCHEMBL3730419 | 0.74 | ICMT (0.41) | ICMTHPGDTSHRHSD17B10GPR88 | |
| SCHEMBL616557 | 0.72 | NR1H4 (0.39) | ICMTHPGDTSHRHSD17B10TP53 | |
| SCHEMBL616773 | 0.72 | ICMT (0.40) | ICMTHPGDTSHRHSD17B10TP53 | |
| SCHEMBL6326477 | 0.72 | HDAC3 (0.67) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL12985206 | 0.72 | EPHX2 (0.50) | CYP19A1HRH4HRH3GPR88GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1682537-B1 | MODULATORS OF CELLULAR ADHESION | SARCODE BIOSCIENCE INC (US) | 2012-03-28 | — | — | EP | disclosed |