Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15457519 | 0.85 | SMN1; SMN2 (0.52) | SMN1; SMN2MEN1KMT2ATSHRGAA | |
| SCHEMBL8793705 | 0.84 | GAA (0.51) | SMN1; SMN2MEN1KMT2ATSHRGAA | |
| SCHEMBL10917680 | 0.82 | GAA (0.45) | SMN1; SMN2MEN1KMT2ATSHRGAA | |
| SCHEMBL26985257 | 0.81 | SMN1; SMN2 (0.57) | SMN1; SMN2MEN1KMT2ATSHRGAA | |
| SCHEMBL1901074 | 0.78 | ALDH1A1 (0.47) | SMN1; SMN2MEN1KMT2ATSHRGAA | |
| SCHEMBL1901070 | 0.78 | ALDH1A1 (0.47) | SMN1; SMN2MEN1KMT2ATSHRGAA | |
| SCHEMBL19295462 | 0.73 | SMN1; SMN2 (0.65) | SMN1; SMN2MEN1KMT2ATSHRGAA | |
| SCHEMBL9751480 | 0.72 | GAA (0.38) | SMN1; SMN2TSHRGAAALOX12ALDH1A1 | |
| SCHEMBL9396153 | 0.72 | ALDH1A1 (0.76) | MEN1KMT2ATSHRGAAALDH1A1 | |
| SCHEMBL9751435 | 0.70 | GAA (0.37) | TSHRGAAALOX12ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5696050-A | APPLYING TO CROP PLANT, SEED OR SURROUNDING SOIL OR WATER ANTIDOTAL AMOUNT OF PLANT SAFENING AGENT | AMERICAN CYANAMID COMPANY (US) | 1997-12-09 | — | — | US | disclosed |
| EP-0613618-B1 | Method for safening herbicides in crops using substituted benzopyran and tetrahydronaphthalene compounds | AMERICAN CYANAMID CO (US) | 1997-04-16 | — | — | EP | disclosed |
| US-5516918-A | PLANT SAFTENING AGENTS USING BENZOPYRAN-4-ACETIC ACIDS OR BENZOTHIOPYRAN-4-ACETIC ACIDS | AMERICAN CYANAMID COMPANY (US) | 1996-05-14 | — | — | US | disclosed |
| US-5407897-A | Plant safening agents | AMERICAN CYANAMID COMPANY (US) | 1995-04-18 | — | — | US | disclosed |
| EP-0613618-A1 | Method for safening herbicides in crops using substituted benzopyran and tetrahydronaphthalene compounds | AMERICAN CYANAMID COMPANY (US) | 1994-09-07 | — | — | EP | disclosed |