Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9751435 | 0.93 | GAA (0.37) | GAAHSD17B10TSHRKDM4EALDH1A1 | |
| SCHEMBL9751429 | 0.84 | GAA (0.39) | GAAHSD17B10TSHRKDM4EALDH1A1 | |
| SCHEMBL9751369 | 0.83 | KDM4E (0.31) | TSHRKDM4EALDH1A1POLBMAPT | |
| SCHEMBL9751420 | 0.81 | GAA (0.36) | GAAHSD17B10TSHRKDM4EALDH1A1 | |
| SCHEMBL9751419 | 0.73 | ALDH1A1 (0.34) | KDM4EALDH1A1 | |
| SCHEMBL8793906 | 0.72 | SMN1; SMN2 (0.52) | GAAHSD17B10TSHRKDM4EALDH1A1 | |
| SCHEMBL9751501 | 0.68 | ALDH1A1 (0.33) | KDM4EALDH1A1 | |
| SCHEMBL8793705 | 0.67 | GAA (0.51) | GAAHSD17B10TSHRKDM4EALDH1A1 | |
| SCHEMBL9396153 | 0.66 | ALDH1A1 (0.76) | GAAHSD17B10TSHRKDM4EALDH1A1 | |
| SCHEMBL10917680 | 0.66 | GAA (0.45) | GAAHSD17B10TSHRKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0422040-A4 | HERBICIDAL BICYCLIC 1,3-DIKETONE DERIVATIVES | — | 1991-08-07 | — | — | EP | claimed |
| EP-0422040-A1 | HERBICIDAL BICYCLIC 1,3-DIKETONE DERIVATIVES | DUNLENA PTY. LIMITED (AU) | 1991-04-17 | — | — | EP | claimed |
| WO-1989012041-A1 | HERBICIDAL BICYCLIC 1,3-DIKETONE DERIVATIVES | DUNLENA PTY. LIMITED (AU) | 1989-12-14 | — | — | WO | claimed |
| EP-0422040-A4 | HERBICIDAL BICYCLIC 1,3-DIKETONE DERIVATIVES | — | 1991-08-07 | — | — | EP | disclosed |
| EP-0422040-A1 | HERBICIDAL BICYCLIC 1,3-DIKETONE DERIVATIVES | DUNLENA PTY. LIMITED (AU) | 1991-04-17 | — | — | EP | disclosed |
| WO-1989012041-A1 | HERBICIDAL BICYCLIC 1,3-DIKETONE DERIVATIVES | DUNLENA PTY. LIMITED (AU) | 1989-12-14 | — | — | WO | disclosed |