SCHEMBL8794441

SCHEMBL8794441

NC(=O)C1C2CCC(C2)C1CO

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.31
GRM2 Q14416 1/20 0.31
GRM3 Q14832 1/20 0.31
GRM8 O00222 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2549796 0.81 LMNA (0.33)
SCHEMBL10798262 0.80 LMNA (0.40) GRM2GRM3GRM8
SCHEMBL3764733 0.73 MEN1 (0.37)
SCHEMBL8795414 0.73 LMNA (0.44)
SCHEMBL6078829 0.73 MEN1 (0.37)
SCHEMBL24516573 0.73 MEN1 (0.37)
SCHEMBL3774101 0.73 MEN1 (0.37)
SCHEMBL6078824 0.73 MEN1 (0.37)
SCHEMBL9606081 0.72
SCHEMBL11421394 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0557519-B1 PROCESS FOR PREPARING SULFONAMIDE DERIVATIVE OF NORBORNANE SHIONOGI & CO (JP) 1997-06-04 EP disclosed
EP-0557519-A1 PROCESS FOR PREPARING SULFONAMIDE DERIVATIVE OF NORBORNANE SHIONOGI & CO., LTD. (JP) 1993-09-01 EP disclosed
US-5124462-A PREPARATION OF NORBORNYL SULFONAMIDE DERIVATIVES SHIONGI & CO., LTD. (JP) 1992-06-23 US disclosed