Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.39 |
| ▸ | GRM8 | O00222 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14613615 | 0.80 | ALDH1A1 (0.40) | LMNATAAR1KMT2AALDH1A1MEN1 | |
| SCHEMBL9873866 | 0.80 | HSD11B1 (0.48) | LMNATAAR1KMT2AALDH1A1MEN1 | |
| SCHEMBL9873869 | 0.80 | HSD11B1 (0.48) | LMNATAAR1KMT2AALDH1A1MEN1 | |
| SCHEMBL8794441 | 0.80 | SMN1; SMN2 (0.31) | GRM2GRM3GRM8 | |
| SCHEMBL23176525 | 0.80 | LMNA (0.52) | LMNATAAR1KMT2AALDH1A1MEN1 | |
| SCHEMBL187221 | 0.80 | LMNA (0.52) | LMNATAAR1KMT2AALDH1A1MEN1 | |
| SCHEMBL14433686 | 0.80 | LMNA (0.52) | LMNATAAR1KMT2AALDH1A1MEN1 | |
| SCHEMBL3045980 | 0.80 | LMNA (0.52) | LMNATAAR1KMT2AALDH1A1MEN1 | |
| SCHEMBL3031493 | 0.80 | LMNA (0.52) | LMNATAAR1KMT2AALDH1A1MEN1 | |
| SCHEMBL23698034 | 0.80 | LMNA (0.52) | LMNATAAR1KMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4649214-A | 5(6)-hydroxymethyl-norbornane-2-carboxylic acid esters and polyurethanes prepared therefrom | HENKEL CORPORATION (US) | 1987-03-10 | — | — | US | disclosed |