Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8794688 | 0.84 | KCNH2 (0.31) | KCNH2 | |
| SCHEMBL4386386 | 0.80 | KCNH2 (0.37) | KCNH2SMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL8794267 | 0.80 | — | — | |
| SCHEMBL4392943 | 0.78 | — | — | |
| SCHEMBL4386239 | 0.78 | KCNH2 (0.31) | KCNH2HRH3 | |
| SCHEMBL4392036 | 0.77 | KCNH2 (0.33) | KCNH2HRH3 | |
| SCHEMBL27647098 | 0.74 | PDIA6 (0.34) | KCNH2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL4380966 | 0.74 | NQO1 (0.45) | KCNH2SMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL7987297 | 0.74 | HRH3 (0.54) | KCNH2HSD17B10SMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL4392060 | 0.73 | ALDH1A1 (0.49) | HSD17B10SMN1; SMN2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760811-A1 | IMIDAZOLE DERIVATIVES AS HISTAMINE RECEPTOR H 3? (ANT)AGONISTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1997-03-12 | — | — | EP | claimed |
| WO-1996029315-A2 | IMIDAZOLE DERIVATIVES AS HISTAMINE RECEPTOR H3 (ANT)AGONISTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 1996-09-26 | — | — | WO | claimed |