SCHEMBL879500

SCHEMBL879500

Sc1ccc(C2CCCCC2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.44
LMNA P02545 1/20 0.44
HDAC8 Q9BY41 2/20 0.44
HDAC6 Q9UBN7 2/20 0.44
HDAC1 Q13547 1/20 0.44
KMT2A Q03164 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
NOTUM Q6P988 2/20 0.43
GAA P10253 2/20 0.43
MAPT P10636 2/20 0.43
HSP90AA1 P07900 1/20 0.43
CYP11B2 P19099 1/20 0.42
HAO1 Q9UJM8 2/20 0.42
ESR2 Q92731 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.40
KDM4E B2RXH2 1/20 0.40
GLA P06280 1/20 0.40
HIF1A Q16665 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
ACMSD Q8TDX5 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6348093 0.97 HDAC1 (0.45) HTTLMNAHDAC8HDAC6HDAC1
SCHEMBL2051518 0.87 ESR2 (0.46) ESR2RAB9ASLC18A3
SCHEMBL8827138 0.87 ESR2 (0.46) ESR2RAB9ASLC18A3
SCHEMBL21891974 0.87 LMNA (0.40) HTTLMNAHDAC8HDAC6HDAC1
SCHEMBL6275125 0.87 HDAC8 (0.52) HTTLMNAHDAC8HDAC6HDAC1
SCHEMBL15260520 0.87 HDAC8 (0.52) HTTLMNAHDAC8HDAC6HDAC1
SCHEMBL28584923 0.87 HDAC8 (0.52) HTTLMNAHDAC8HDAC6HDAC1
SCHEMBL42782 0.87 HDAC8 (0.52) HTTLMNAHDAC8HDAC6HDAC1
SCHEMBL21189421 0.84 CYP3A4 (0.41) HTTLMNAHDAC8HDAC6HDAC1
SCHEMBL5146632 0.84 ESR2 (0.52) HTTLMNAHDAC8HDAC6HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 153 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114423742-B Benzotriazole-based compound, light absorber and resin composition 三井化学株式会社 2024-05-28 CN claimed
EP-1807072-B1 CYCLOALKYL LACTAM DERIVATIVES AS INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE 1 LILLY CO ELI (US) 2009-01-07 EP claimed
CN-114423742-B Benzotriazole-based compound, light absorber and resin composition 三井化学株式会社 2024-05-28 CN disclosed
CN-117466830-A Benzotriazole-based compound, light absorber and resin composition 三井化学株式会社 2024-01-30 CN disclosed
WO-2024005030-A1 DIPHENYLETHENE-BASED COMPOUND, LIGHT ABSORBER, RESIN COMPOSITION, AND USE THEREOF 山本化成株式会社 2024-01-04 WO disclosed
US-11681222-B2 Fluorine-containing polymer, purification method, and radiation-sensitive resin composition JSR CORPORATION (JP) 2023-06-20 US disclosed
CN-110637006-B Process for producing carbonate derivative 国立大学法人神户大学 2022-05-24 CN disclosed
CN-114423742-A Benzotriazole compound, light absorber, and resin composition 三井化学株式会社 2022-04-29 CN disclosed
CN-111801388-B High refractive composition, high refractive film, and method for manufacturing high refractive film 株式会社LG化学 2022-04-01 CN disclosed
CN-109554122-B Curing adhesive for polarizing film, optical film, and image display device 日东电工株式会社 2022-03-01 CN disclosed
EP-3611175-B1 NAPHTHALOCYANINE COMPOUND, METHOD FOR PRODUCING SAME, AND USE THEREOF YAMAMOTO CHEMICALS INC (JP) 2022-02-09 EP disclosed
US-4670592-A BACTERICIDES, FUNGICIDES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1987-06-02 US disclosed
EP-0093922-B1 BENZOXAZIN-2-ONES, THEIR PREPARATION AND THERAPEUTIC AGENTS CONTAINING THESE COMPOUNDS Dr. Karl Thomae GmbH (DE) 1986-12-30 EP disclosed
US-4629733-A CARDIOVASCULAR DISORDERS DR. KARL THOMAE GMBH (DE) 1986-12-16 US disclosed
US-4518597-A THROMBOSIS, ARTERIOSCLEROSIS, ANTITUMOR, ANTICOAGULANTS DR. KARL THOMAE GMBH (DE) 1985-05-21 US disclosed
EP-0103095-A2 Dichroic material containing anthraquinone dyes BAYER AG (DE) 1984-03-21 EP disclosed
EP-0093922-A2 Benzoxazin-2-ones, their preparation and therapeutic agents containing these compounds Dr. Karl Thomae GmbH (DE) 1983-11-16 EP disclosed
EP-0003771-B1 CARBOSTYRILE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM Dr. Karl Thomae GmbH (DE) 1982-10-20 EP disclosed
US-4329347-A Cardiotonic and antithrombotic sulfur-containing derivatives of carbostyril BOEHRINGER INGELHEIM GMBH (DE) 1982-05-11 US disclosed
EP-0003771-A1 Carbostyrile derivatives, their preparation and pharmaceutical compositions containing them Dr. Karl Thomae GmbH (DE) 1979-09-05 EP disclosed