Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 2/20 | 0.42 |
| ▸ | EDNRA | P25101 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8795041 | 0.91 | EDNRB (0.44) | EDNRBEDNRANPSR1TSHRALDH1A1 | |
| SCHEMBL1111522 | 0.78 | POLB (0.47) | NPSR1TSHRALDH1A1KMT2APOLB | |
| SCHEMBL8795075 | 0.77 | EDNRB (0.46) | EDNRBEDNRANPSR1TSHRALDH1A1 | |
| SCHEMBL743035 | 0.76 | NPSR1 (0.40) | NPSR1TSHRALDH1A1KMT2APOLB | |
| SCHEMBL8794905 | 0.76 | TSHR (0.49) | NPSR1TSHRALDH1A1KMT2APOLB | |
| SCHEMBL8794923 | 0.75 | S1PR1 (0.43) | NPSR1TSHRALDH1A1KMT2APOLB | |
| SCHEMBL8795346 | 0.75 | HIF1A (0.45) | NPSR1TSHRALDH1A1KMT2APOLB | |
| SCHEMBL1577217 | 0.74 | KMT2A (0.45) | EDNRBEDNRANPSR1TSHRALDH1A1 | |
| SCHEMBL19714098 | 0.73 | NPSR1 (0.40) | NPSR1TSHRALDH1A1KMT2APOLB | |
| SCHEMBL8626603 | 0.73 | RXRA (0.41) | EDNRBEDNRANPSR1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0645386-B1 | N-Azinyl-N'-(het)arylsulfonylureas as herbicides | BAYER AG (DE) | 1997-12-29 | — | — | EP | disclosed |
| EP-0645386-A1 | N-Azinyl-N'-(het)arylsulfonylureas as herbicides | BAYER AG (DE) | 1995-03-29 | — | — | EP | disclosed |