Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8795091 | 0.88 | ALDH1A1 (0.44) | HIF1AGAANPSR1ALDH1A1HTT | |
| SCHEMBL9177288 | 0.86 | HIF1A (0.41) | HIF1AGAANPSR1ALDH1A1HTT | |
| SCHEMBL8795075 | 0.84 | EDNRB (0.46) | GAANPSR1ALDH1A1HTTMAPT | |
| SCHEMBL8795096 | 0.83 | NPSR1 (0.47) | NPSR1ALDH1A1HTTLMNAMAPT | |
| SCHEMBL8626603 | 0.79 | RXRA (0.41) | GAANPSR1ALDH1A1HTTMAPT | |
| SCHEMBL8795039 | 0.79 | EDNRB (0.46) | NPSR1MAPTKMT2ANPC1MEN1 | |
| SCHEMBL8634474 | 0.77 | EDNRB (0.39) | HIF1AGAANPSR1ALDH1A1HTT | |
| SCHEMBL8630925 | 0.76 | LMNA (0.43) | HIF1AGAANPSR1ALDH1A1HTT | |
| SCHEMBL8795221 | 0.75 | EDNRB (0.42) | NPSR1ALDH1A1HTTTDP1KMT2A | |
| SCHEMBL8795165 | 0.75 | NPSR1 (0.42) | NPSR1ALDH1A1HTTLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0645386-B1 | N-Azinyl-N'-(het)arylsulfonylureas as herbicides | BAYER AG (DE) | 1997-12-29 | — | — | EP | disclosed |
| EP-0645386-A1 | N-Azinyl-N'-(het)arylsulfonylureas as herbicides | BAYER AG (DE) | 1995-03-29 | — | — | EP | disclosed |