Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATP4A | P20648 | 2/20 | 0.37 |
| ▸ | ATP4B | P51164 | 2/20 | 0.37 |
| ▸ | PPARD | Q03181 | 13/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7489067 | 0.89 | MAPT (0.41) | MAPTMEN1ALDH1A1OPRK1KMT2A | |
| SCHEMBL7024314 | 0.85 | FFAR1 (0.41) | ATP4AATP4BPPARDNR1H4FFAR1 | |
| SCHEMBL8794428 | 0.82 | PPARG (0.41) | MAPTMEN1ALDH1A1OPRK1KMT2A | |
| SCHEMBL8794374 | 0.79 | FFAR1 (0.60) | MAPTPPARDFFAR1 | |
| SCHEMBL7162944 | 0.77 | FFAR1 (0.59) | MAPTPPARDFFAR1 | |
| SCHEMBL8888020 | 0.76 | LTA4H (0.49) | MEN1KMT2AFFAR1 | |
| SCHEMBL7164840 | 0.76 | FFAR1 (0.58) | MAPTPPARDFFAR1 | |
| SCHEMBL8888862 | 0.75 | MGLL (0.50) | MEN1KMT2AFFAR1 | |
| SCHEMBL8888514 | 0.75 | MGLL (0.50) | MEN1KMT2AFFAR1 | |
| SCHEMBL8888610 | 0.75 | MGLL (0.50) | MEN1KMT2AFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0612743-B1 | Oxazolidinedione derivatives, their production and use in lowering blood sugar and lipid levels | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-09-10 | — | — | EP | claimed |
| US-5665748-A | ANTIDIABETIC, HYPOLIPIDEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-09-09 | — | — | US | claimed |
| EP-0612743-A1 | Oxazolidinedione derivatives, their production and use in lowering blood sugar and lipid levels | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-08-31 | — | — | EP | claimed |