SCHEMBL8795482

SCHEMBL8795482

O=C(O)N(c1ccccc1)S(=O)(=O)c1ccsc1C1=NOCCO1

nearest known ligand 0.33

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.33
CDK1 P06493 1/20 0.31
CCNB1 P14635 1/20 0.31
CCNA2 P20248 1/20 0.31
CCND1 P24385 1/20 0.31
CDK2 P24941 1/20 0.31
CDK7 P50613 1/20 0.31
CCNH P51946 1/20 0.31
CCNA1 P78396 1/20 0.31
CDK6 Q00534 1/20 0.31
GLA P06280 1/20 0.31
POLB P06746 1/20 0.30
EDNRA P25101 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8794389 0.81 ATM (0.32) CDK1CCNB1CCNA2CCND1CDK2
SCHEMBL1577054 0.81 NPSR1 (0.32) NPSR1CDK1CCNB1CCNA2CCND1
SCHEMBL7911326 0.74
SCHEMBL8631312 0.74 CA2 (0.32) NPSR1EDNRA
SCHEMBL8795588 0.73
SCHEMBL8795395 0.72 L3MBTL1 (0.31)
SCHEMBL8794814 0.70 HSP90AA1 (0.30)
SCHEMBL8795803 0.70
SCHEMBL8633923 0.62 PTPRC (0.44) POLB
SCHEMBL7643240 0.61 NPSR1 (0.55) NPSR1CDK1CCNB1CCNA2CCND1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0645386-B1 N-Azinyl-N'-(het)arylsulfonylureas as herbicides BAYER AG (DE) 1997-12-29 EP disclosed
EP-0801649-A2 HYDROXYLAMINE DERIVATIVES USEFUL FOR ENHANCING THE MOLECULAR CHAPERON PRODUCTION AND THE PREPARATION THEREOF BIOREX KUTATO ES FEJLESZTÖ RT. (HU) 1997-10-22 EP disclosed
WO-1997016439-A1 HYDROXYLAMINE DERIVATIVES USEFUL FOR ENHANCING THE MOLECULAR CHAPERON PRODUCTION AND THE PREPARATION THEREOF Biorex Kutató és Fejlesztó Rt. (HU) 1997-05-09 WO disclosed
EP-0645386-A1 N-Azinyl-N'-(het)arylsulfonylureas as herbicides BAYER AG (DE) 1995-03-29 EP disclosed