Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 7/20 | 0.34 |
| ▸ | CA2 | P00918 | 7/20 | 0.34 |
| ▸ | CA9 | Q16790 | 5/20 | 0.34 |
| ▸ | CA12 | O43570 | 4/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | PDE5A | O76074 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8795239 | 0.86 | GAA (0.36) | POLBMAPTKDM4EMEN1KMT2A | |
| SCHEMBL8795506 | 0.84 | POLB (0.36) | POLBMAPTKDM4EMEN1KMT2A | |
| SCHEMBL8794942 | 0.84 | ALDH1A1 (0.34) | POLBMAPTKDM4EMEN1KMT2A | |
| SCHEMBL8793993 | 0.82 | EGFR (0.34) | POLBMAPTKDM4EMEN1KMT2A | |
| SCHEMBL8795244 | 0.80 | POLB (0.36) | POLBMAPTKDM4EMEN1KMT2A | |
| SCHEMBL8794947 | 0.79 | L3MBTL1 (0.36) | POLBMAPTKDM4EMEN1KMT2A | |
| SCHEMBL29442980 | 0.77 | EGFR (0.34) | POLBMAPTKDM4ECA1CA2 | |
| SCHEMBL8793999 | 0.77 | EGFR (0.34) | POLBMAPTKDM4ECA1CA2 | |
| SCHEMBL9566804 | 0.76 | MAPT (0.36) | POLBMAPTKDM4EMEN1KMT2A | |
| SCHEMBL8796400 | 0.75 | ALDH1A1 (0.38) | POLBCA1CA2CA9HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0541807-B1 | NOVEL BENZOPYRAN DERIVATIVE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 1997-12-17 | — | — | EP | disclosed |
| US-5412117-A | Potassium channel activators, antiasmatics, antiepileptics | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0541807-A1 | NOVEL BENZOPYRAN DERIVATIVE | Chugai Seiyaku Kabushiki Kaisha (JP) | 1993-05-19 | — | — | EP | disclosed |