SCHEMBL8795642

SCHEMBL8795642

CC1CNc2c(N)cnn2C1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SMPD3 Q9NY59 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24439554 0.67
Hydrochloric Acid SCHEMBL8156603 0.64
SCHEMBL17476303 0.63
SCHEMBL20253509 0.62
SCHEMBL26988262 0.60 SCN9A (0.32)
SCHEMBL26989546 0.60 SCN9A (0.32)
SCHEMBL20253510 0.59 NUDT1 (0.31)
SCHEMBL20828043 0.59 LRRK2 (0.42) SMPD3
SCHEMBL26989599 0.57 GRM2 (0.33)
SCHEMBL26988705 0.57 GRM2 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0562061-B1 HAIR-DYEING AGENT CONTAINING AMINOPYRAZOLE DERIVATIVES, AND NEW PYRAZOLE DERIVATIVES WELLA AG (DE) 1997-01-22 EP claimed
US-5380340-A Hair dye containing aminopyrazole derivatives as well as pyrazole derivatives WELLA AKTIENGESELLSCHAFT (DE) 1995-01-10 US claimed
EP-0576350-B1 Branched alkylamino thiazole derivatives, process for their preparation and pharmaceutical compositions containing them SANOFI SA (FR) 1997-10-29 EP disclosed
EP-0562061-B1 HAIR-DYEING AGENT CONTAINING AMINOPYRAZOLE DERIVATIVES, AND NEW PYRAZOLE DERIVATIVES WELLA AG (DE) 1997-01-22 EP disclosed
US-5380340-A Hair dye containing aminopyrazole derivatives as well as pyrazole derivatives WELLA AKTIENGESELLSCHAFT (DE) 1995-01-10 US disclosed