Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 10/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 9/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.42 |
| ▸ | RXRG | P48443 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27828872 | 0.87 | POLB (0.54) | POLBFFAR4FFAR1 | |
| SCHEMBL7813393 | 0.85 | POLB (0.51) | POLBFFAR4NPSR1 | |
| SCHEMBL4013922 | 0.84 | POLB (0.51) | POLBFFAR4FFAR1 | |
| SCHEMBL2431545 | 0.84 | CYP4F2 (0.49) | POLBNPSR1 | |
| SCHEMBL7366498 | 0.81 | POLB (0.51) | POLBFFAR4FFAR1 | |
| SCHEMBL12070734 | 0.81 | POLB (0.48) | POLBFFAR4FFAR1 | |
| SCHEMBL8796401 | 0.80 | NPSR1 (0.48) | POLBFFAR4FFAR1NPSR1 | |
| SCHEMBL17743971 | 0.79 | POLB (0.49) | POLBFFAR4FFAR1NPSR1 | |
| SCHEMBL12070041 | 0.79 | POLB (0.51) | POLBFFAR4FFAR1NPSR1 | |
| SCHEMBL11708826 | 0.78 | FFAR4 (0.44) | POLBFFAR4RXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0783518-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO. INC. (US) | 1997-07-16 | — | — | EP | disclosed |