Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.44 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31114215 | 0.89 | PPARA (0.51) | LMNAFFAR4PPARALTB4RLTB4R2 | |
| SCHEMBL6112752 | 0.89 | PPARA (0.51) | LMNAFFAR4PPARALTB4RLTB4R2 | |
| SCHEMBL27828872 | 0.85 | POLB (0.54) | POLBLMNAFFAR4FFAR1 | |
| SCHEMBL28295331 | 0.84 | KMT2A (0.41) | CA12CA1CA2CA7CA9 | |
| SCHEMBL3234088 | 0.83 | CXCL8 (0.53) | POLBLMNACA12CA1CA2 | |
| SCHEMBL362209 | 0.83 | LMNA (0.59) | POLBLMNAFFAR1NPSR1SMN1; SMN2 | |
| SCHEMBL29590071 | 0.83 | LMNA (0.59) | POLBLMNAFFAR1NPSR1SMN1; SMN2 | |
| SCHEMBL3691207 | 0.82 | ALOX5 (0.59) | POLBLMNAFFAR1CA12CA1 | |
| SCHEMBL490691 | 0.82 | CTSG (0.56) | LMNAFFAR4CA12CA1CA2 | |
| SCHEMBL3954801 | 0.82 | LMNA (0.50) | POLBLMNAFFAR4FFAR1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3020717-B1 | P2X4 RECEPTOR ANTAGONIST | NIPPON CHEMIPHAR CO (JP) | 2021-12-15 | — | — | EP | disclosed |
| US-9873683-B2 | P2X4 receptor antagonist | NIPPON CHEMIPHAR CO., LTD (JP) | 2018-01-23 | — | — | US | disclosed |
| US-9840497-B2 | — | — | 2017-12-12 | — | — | US | disclosed |
| US-20160244434-A1 | P2X4 RECEPTOR ANTAGONIST | NIPPON CHEMIPHAR CO., LTD. (JP) | 2016-08-25 | — | — | US | disclosed |
| EP-3020717-A1 | P2X4 RECEPTOR ANTAGONIST | Nippon Chemiphar Co., Ltd. (JP) | 2016-05-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160244434-A1 | P2X4 RECEPTOR ANTAGONIST | P2RX1, P2RX7, P2RX2 | POLB 4442/4885LMNA 1239/4885FFAR4 561/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.