Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 8/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 6/20 | 0.46 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4013922 | 0.88 | POLB (0.51) | POLBFFAR1FFAR4STING1LMNA | |
| SCHEMBL27828872 | 0.87 | POLB (0.54) | POLBFFAR1FFAR4LMNA | |
| SCHEMBL27828902 | 0.86 | POLB (0.53) | POLBFFAR1FFAR4 | |
| SCHEMBL490405 | 0.85 | AOC3 (0.53) | POLBFFAR1FFAR4KDM4EMAPT | |
| SCHEMBL10618516 | 0.84 | HSD17B10 (0.53) | STING1KDM4EMAPTTDP1ALDH1A1 | |
| SCHEMBL31674134 | 0.83 | MEP1B (0.53) | POLBFFAR1FFAR4KDM4ETDP1 | |
| SCHEMBL21317656 | 0.83 | TDP1 (0.54) | POLBFFAR1FFAR4KDM4EMAPT | |
| SCHEMBL29999191 | 0.83 | TDP1 (0.54) | POLBFFAR1FFAR4KDM4EMAPT | |
| SCHEMBL7285138 | 0.82 | PTGER1 (0.49) | POLBKDM4EMAPTPTGER1 | |
| SCHEMBL8795706 | 0.81 | POLB (0.51) | POLBFFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0237929-B1 | 3,5-DISUBSTITUTED PYROCATECHOL DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1993-06-02 | — | — | EP | disclosed |
| EP-0237929-A1 | 3,5-Disubstituted pyrocatechol derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1987-09-23 | — | — | EP | disclosed |