Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 2/20 | 0.48 |
| ▸ | MC1R | Q01726 | 2/20 | 0.48 |
| ▸ | CCKBR | P32239 | 9/20 | 0.46 |
| ▸ | CCKAR | P32238 | 8/20 | 0.46 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | BRD2 | P25440 | 1/20 | 0.43 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.43 |
| ▸ | OXTR | P30559 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8797563 | 0.84 | MC4R (0.47) | MC4RMC1RCCKBRCCKARALDH1A1 | |
| SCHEMBL8795334 | 0.82 | SENP1 (0.54) | CCKBRCCKARSENP1BRD4BRD2 | |
| SCHEMBL9302112 | 0.82 | SENP1 (0.53) | CCKBRSENP1BRD4BRD2BRD3 | |
| SCHEMBL9008787 | 0.82 | SENP1 (0.53) | CCKBRSENP1BRD4BRD2BRD3 | |
| SCHEMBL9301274 | 0.82 | SENP1 (0.53) | CCKBRSENP1BRD4BRD2BRD3 | |
| SCHEMBL9008789 | 0.82 | SENP1 (0.53) | CCKBRSENP1BRD4BRD2BRD3 | |
| SCHEMBL9008788 | 0.82 | SENP1 (0.53) | CCKBRSENP1BRD4BRD2BRD3 | |
| SCHEMBL9302105 | 0.82 | SENP1 (0.53) | CCKBRSENP1BRD4BRD2BRD3 | |
| SCHEMBL8798046 | 0.81 | SENP1 (0.52) | CCKBRCCKARSENP1BRD4BRD2 | |
| SCHEMBL9303317 | 0.80 | SENP1 (0.56) | CCKBRSENP1BRD4BRD2BRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755394-A1 | A METHOD OF INDUCING CHOLECYSTOKININ AGONIST ACTIVITY USING 1,4-BENZODIAZEPINE COMPOUNDS | GLAXO WELLCOME INC. (US) | 1997-01-29 | — | — | EP | disclosed |
| WO-1995028399-A1 | A METHOD OF INDUCING CHOLECYSTOKININ AGONIST ACTIVITY USING 1,4-BENZODIAZEPINE COMPOUNDS | GLAXO WELLCOME INC. (US) | 1995-10-26 | — | — | WO | disclosed |