Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 4/20 | 0.34 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.34 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8795400 | 0.87 | MEN1 (0.44) | ALDH1A1KMT2AMEN1NPSR1CYP2C9 | |
| SCHEMBL8796921 | 0.87 | SMN1; SMN2 (0.36) | ALDH1A1KMT2AMAPTCACNA1HHPGD | |
| SCHEMBL7957823 | 0.86 | ALDH1A1 (0.35) | ALDH1A1KMT2AMEN1NPSR1CYP2C9 | |
| SCHEMBL7964339 | 0.86 | ALDH1A1 (0.35) | ALDH1A1KMT2AMEN1NPSR1CYP2C9 | |
| SCHEMBL8796230 | 0.86 | KMT2A (0.34) | ALDH1A1KMT2AMEN1CACNA1HHPGD | |
| SCHEMBL8796360 | 0.85 | MEN1 (0.35) | KMT2AMEN1NPSR1MAPTLMNA | |
| SCHEMBL8796255 | 0.84 | LMNA (0.34) | ALDH1A1KMT2ALMNACACNA1HHPGD | |
| SCHEMBL8796388 | 0.81 | HPGD (0.35) | ALDH1A1KMT2AMEN1LMNACACNA1H | |
| Bicarbonate SCHEMBL6991552 | 0.79 | MEN1 (0.44) | ALDH1A1KMT2AMEN1S1PR5SIGMAR1 | |
| SCHEMBL8796950 | 0.78 | HPGD (0.37) | ALDH1A1KMT2AMEN1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754175-A1 | ALKOXY-ALKYL-SUBSTITUTED 1-H-3-ARYL-PYRROLIDINE-2,4-DIONES USED AS HERBICIDES AND PESTICIDES | BAYER AG (DE) | 1997-01-22 | — | — | EP | disclosed |