Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 3/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 5/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | GAPDH | P04406 | 1/20 | 0.37 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL879638 | 0.83 | PGR (0.44) | TDP2CYP3A4CYP2C9 | |
| SCHEMBL10291449 | 0.83 | NISCH (0.47) | MAOB | |
| SCHEMBL879700 | 0.83 | KMT2A (0.41) | TDP2METAP2CHRNB4CHRNA3MAOB | |
| SCHEMBL10291448 | 0.83 | NISCH (0.47) | MAPKAPK2 | |
| SCHEMBL16302129 | 0.82 | CNR1 (0.30) | — | |
| SCHEMBL2426716 | 0.82 | SIGMAR1 (0.42) | CYP3A4CYP2C9 | |
| SCHEMBL13553312 | 0.81 | MAOB (0.49) | MAOB | |
| Hydrochloric Acid SCHEMBL2422663 | 0.80 | SIGMAR1 (0.44) | CYP3A4 | |
| SCHEMBL879693 | 0.80 | MAPKAPK2 (0.45) | MAPKAPK2 | |
| SCHEMBL879645 | 0.80 | NISCH (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010126030-A1 | SPIROIMIDAZOLONE DERIVATIVE | 中外製薬株式会社 (JP) | 2010-11-04 | — | — | WO | disclosed |