Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23234710 | 0.87 | ALDH1A1 (0.34) | GAAPOLBGFERALDH1A1HTT | |
| SCHEMBL5381501 | 0.83 | CA1 (0.32) | CA1CA2GAAPOLBGFER | |
| SCHEMBL5381511 | 0.77 | POLB (0.32) | GAAPOLBGFER | |
| SCHEMBL9181900 | 0.76 | CA1 (0.31) | CA1CA2GAAPOLBGFER | |
| SCHEMBL8797567 | 0.74 | ALDH1A1 (0.46) | CA2POLBALDH1A1HTT | |
| SCHEMBL2155116 | 0.74 | ALDH1A1 (0.38) | SLC6A2CA1CA2GAAPOLB | |
| SCHEMBL461449 | 0.74 | CA1 (0.55) | SLC6A2CA1CA2GAAPOLB | |
| SCHEMBL16706079 | 0.73 | CA1 (0.30) | CA1CA2 | |
| Hydrochloric Acid SCHEMBL5431425 | 0.72 | GAA (0.38) | SLC6A2CA1CA2GAAPOLB | |
| SCHEMBL29926096 | 0.72 | CA1 (0.52) | SLC6A2CA1CA2GAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497201-B1 | Tricyclic compounds and intermediates thereof | KYOWA HAKKO KOGYO KK (JP) | 1997-01-15 | — | — | EP | disclosed |
| US-5478835-A | Acyl coenzyme A: acyltransferase inhibitors; treatment of hyperlipemia and arteriosclerosis | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1995-12-26 | — | — | US | disclosed |
| US-5340807-A | Tricyclic compounds and intermediates thereof | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1994-08-23 | — | — | US | disclosed |
| EP-0497201-A1 | Tricyclic compounds and intermediates thereof | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-08-05 | — | — | EP | disclosed |