SCHEMBL2155116

SCHEMBL2155116

CC(C)c1cc(N)cc(C(C)C)c1N

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.38
TSHR P16473 2/20 0.38
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
GAA P10253 3/20 0.35
CYP3A4 P08684 3/20 0.35
MAPT P10636 1/20 0.35
POLB P06746 1/20 0.34
GFER P55789 1/20 0.34
GABRA1 P14867 5/20 0.33
GABRB1 P18505 4/20 0.33
GABRB2 P47870 3/20 0.33
ANPEP P15144 1/20 0.32
LMNA P02545 2/20 0.31
SLC6A2 P23975 2/20 0.31
HTR2B P41595 2/20 0.31
TRPA1 O75762 1/20 0.31
CHRM1 P11229 1/20 0.31
ADRA1A P35348 1/20 0.31
HIF1A Q16665 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5431425 0.97 GAA (0.38) ALDH1A1TSHRCA1CA2GAA
SCHEMBL5160431 0.85 ALDH1A1 (0.40) ALDH1A1TSHRCA1CA2GAA
Hydrochloric Acid SCHEMBL5430513 0.83 POLB (0.41) ALDH1A1TSHRCA1CA2GAA
SCHEMBL461449 0.82 CA1 (0.55) ALDH1A1TSHRCA1CA2GAA
SCHEMBL2154892 0.82 GABRA1 (0.39) ALDH1A1TSHRCA1CA2GAA
SCHEMBL29926096 0.80 CA1 (0.52) ALDH1A1TSHRCA1CA2GAA
SCHEMBL3440745 0.80 GABRA1 (0.50) ALDH1A1CA1CA2GAAMAPT
Methane SCHEMBL27861345 0.80 CA1 (0.52) ALDH1A1TSHRCA1CA2GAA
SCHEMBL17383538 0.80 ALDH1A1 (0.43) ALDH1A1TSHRCA1CA2GAA
SCHEMBL2735032 0.80 NOS2 (0.43) ALDH1A1TSHRCA1CA2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070044254-A1 Novel 2,6-disubstituted primary para-phenylenediamines and process for their use in the oxidation dyeing of keratin fibers L'OREAL S.A. (FR) 2007-03-01 US claimed
EP-1757579-A1 Primary 2,6-disubstituted para-phenylenediamines and their uses for dyeing keratin fibres L'Oréal (FR) 2007-02-28 EP claimed
EP-4269471-A1 COVALENT ORGANIC FRAMEWORK AND CATALYST, PREPARATION METHODS THEREFOR, AND APPLICATIONS THEREOF Zhejiang University (CN) 2023-11-01 EP disclosed
US-11692062-B2 Methods of manufacture for polyetherimide SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2023-07-04 US disclosed
CN-110167992-B Method for producing polyetherimide 高新特殊工程塑料全球技术有限公司 2022-10-18 CN disclosed
EP-3562858-A1 METHODS OF MANUFACTURE FOR POLYETHERIMIDE SABIC Global Technologies B.V. (NL) 2019-11-06 EP disclosed
US-20190309127-A1 METHODS OF MANUFACTURE FOR POLYETHERIMIDE SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2019-10-10 US disclosed
CN-104769505-B Toner, developer, and image forming apparatus 株式会社理光 2019-07-12 CN disclosed
EP-3184171-B1 PHOSPHINYL AMIDINE COMPOUNDS, METAL COMPLEXES, CATALYST SYSTEMS, AND THEIR USE TO OLIGOMERIZE OR POLYMERIZE OLEFINS CHEVRON PHILLIPS CHEMICAL CO LP (US) 2019-03-20 EP disclosed
US-10144752-B2 Phosphinyl amidine compounds, metal complexes, catalyst systems, and their use to oligomerize or polymerize olefins CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2018-12-04 US disclosed
CN-106083927-B Phosphino- amidine compound, metal complex, antigravity system and their oligomeric or olefin polymerization purposes 切弗朗菲利浦化学公司 2018-10-26 CN disclosed
CN-102781949-A Phosphinyl amidine compounds, metal complexes, catalyst systems, and their use for oligomerizing or polymerizing olefins CHEVRON PHILLIPS CHEMICAL CO 2012-11-14 CN disclosed
EP-2519532-A1 PHOSPHINYL AMIDINE COMPOUNDS, METAL COMPLEXES, CATALYST SYSTEMS, AND THEIR USE TO OLIGOMERIZE OR POLYMERIZE OLEFINS Chevron Phillips Chemical Company LP (US) 2012-11-07 EP disclosed
WO-2011082192-A1 PHOSPHINYL AMIDINE COMPOUNDS, METAL COMPLEXES, CATALYST SYSTEMS, AND THEIR USE TO OLIGOMERIZE OR POLYMERIZE OLEFINS CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2011-07-07 WO disclosed
US-20070044254-A1 Novel 2,6-disubstituted primary para-phenylenediamines and process for their use in the oxidation dyeing of keratin fibers L'OREAL S.A. (FR) 2007-03-01 US disclosed
US-20070044254-A1 Novel 2,6-disubstituted primary para-phenylenediamines and process for their use in the oxidation dyeing of keratin fibers L'OREAL S.A. (FR) 2007-03-01 US disclosed
US-20070044254-A1 Novel 2,6-disubstituted primary para-phenylenediamines and process for their use in the oxidation dyeing of keratin fibers L'OREAL S.A. (FR) 2007-03-01 US disclosed
EP-1757579-A1 Primary 2,6-disubstituted para-phenylenediamines and their uses for dyeing keratin fibres L'Oréal (FR) 2007-02-28 EP disclosed
EP-1757579-A1 Primary 2,6-disubstituted para-phenylenediamines and their uses for dyeing keratin fibres L'Oréal (FR) 2007-02-28 EP disclosed
EP-1757579-A1 Primary 2,6-disubstituted para-phenylenediamines and their uses for dyeing keratin fibres L'Oréal (FR) 2007-02-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070044254-A1 Novel 2,6-disubstituted primary para-phenylenediamines and process for their use in the oxidation dyeing of keratin fibers KRT18, DSP, CDC73 ALDH1A1 159/4885TSHR 4704/4885CA1 1795/4885
US-10144752-B2 Phosphinyl amidine compounds, metal complexes, catalyst systems, and their use to oligomerize or polymerize olefins NIT2, NCLN, NPM1 ALDH1A1 4849/4885TSHR 3542/4885CA1 676/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.