Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 5/20 | 0.46 |
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8795886 | 0.96 | MAPK1 (0.47) | MAPK1EGFRALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL8796516 | 0.92 | MAPK1 (0.47) | MAPK1EGFRALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL8795418 | 0.88 | MAPK1 (0.49) | MAPK1EGFRALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL8825801 | 0.86 | MAPK1 (0.64) | MAPK1EGFRALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL8796546 | 0.85 | EGFR (0.51) | MAPK1EGFRALDH1A1KDM4ERXFP1 | |
| SCHEMBL8795310 | 0.85 | AURKA (0.44) | MAPK1EGFRALDH1A1KDM4EPDGFRB | |
| SCHEMBL8795456 | 0.84 | HTT (0.46) | MAPK1EGFRSMN1; SMN2PDGFRBHTT | |
| SCHEMBL8796533 | 0.84 | PIK3CA (0.45) | MAPK1EGFRALDH1A1KDM4EPDGFRB | |
| SCHEMBL8795731 | 0.83 | PIK3CA (0.45) | MAPK1EGFRALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL8796269 | 0.83 | PIK3CA (0.46) | MAPK1EGFRALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758653-A1 | IMIDAZOQUINAZOLINE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-02-19 | — | — | EP | disclosed |