Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 6/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 4/20 | 0.44 |
| ▸ | EGFR | P00533 | 6/20 | 0.43 |
| ▸ | RPS6KB1 | P23443 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8795923 | 0.96 | HTT (0.46) | HTTAURKAAURKBEGFRRPS6KB1 | |
| SCHEMBL8796312 | 0.93 | AURKA (0.49) | HTTAURKAAURKBEGFRRPS6KB1 | |
| SCHEMBL8795310 | 0.91 | AURKA (0.44) | HTTAURKAAURKBEGFRMAPK1 | |
| SCHEMBL8796051 | 0.88 | MEN1 (0.43) | HTTAURKAAURKBEGFRPDGFRB | |
| SCHEMBL8795332 | 0.88 | HTT (0.48) | HTTAURKAAURKBEGFRRPS6KB1 | |
| SCHEMBL8795881 | 0.86 | MEN1 (0.44) | HTTAURKAAURKBEGFRRPS6KB1 | |
| SCHEMBL8825746 | 0.86 | HTT (0.62) | HTTAURKAEGFRRPS6KB1MAPK1 | |
| SCHEMBL8796953 | 0.84 | MAPK1 (0.46) | HTTEGFRMAPK1SMN1; SMN2PDGFRB | |
| SCHEMBL8796055 | 0.83 | RPS6KB1 (0.47) | HTTAURKAEGFRRPS6KB1MAPK1 | |
| SCHEMBL8795099 | 0.83 | MEN1 (0.44) | HTTAURKAEGFRRPS6KB1PDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758653-A1 | IMIDAZOQUINAZOLINE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-02-19 | — | — | EP | disclosed |