Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
| ▸ | KDM4A | O75164 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8796663 | 0.90 | FFAR1 (0.36) | HRH3FFAR1PPARGPOLBALDH1A1 | |
| SCHEMBL8796863 | 0.88 | HRH3 (0.35) | HRH3FFAR1 | |
| SCHEMBL6953755 | 0.85 | HRH3 (0.40) | HRH3FFAR1PPARGCTSK | |
| SCHEMBL8796976 | 0.83 | FFAR1 (0.50) | HRH3FFAR1PPARAPPARGALDH1A1 | |
| SCHEMBL8798105 | 0.81 | HRH3 (0.44) | HRH3FFAR1PPARGPOLBMAPT | |
| SCHEMBL8797027 | 0.80 | HRH3 (0.36) | HRH3FFAR1PPARGPOLBALDH1A1 | |
| SCHEMBL8797744 | 0.80 | HRH3 (0.35) | HRH3FFAR1PPARAPPARGPOLB | |
| SCHEMBL8797111 | 0.80 | HRH3 (0.35) | HRH3FFAR1PPARGPOLBKDM4A | |
| SCHEMBL8797318 | 0.80 | ESR1 (0.37) | — | |
| SCHEMBL8797305 | 0.80 | HRH3 (0.36) | HRH3POLBALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787727-A1 | Benzoazine derivative or salt thereof and pharmaceutical composition comprising the same | SS Pharmaceutical Co., Ltd. (JP) | 1997-08-06 | — | — | EP | disclosed |