Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8798105 | 0.95 | HRH3 (0.44) | HRH3FFAR1PPARGMAOBCTSK | |
| SCHEMBL8797318 | 0.88 | ESR1 (0.37) | — | |
| SCHEMBL8797264 | 0.88 | ROCK2 (0.38) | HRH3FFAR1PPARGMAOBHPGD | |
| SCHEMBL8797305 | 0.88 | HRH3 (0.36) | HRH3MAOBHPGDNPSR1 | |
| SCHEMBL8797566 | 0.88 | HRH3 (0.40) | HRH3FFAR1MAOBHPGDNPSR1 | |
| SCHEMBL8796797 | 0.87 | FFAR1 (0.39) | HRH3FFAR1PPARGMAOB | |
| SCHEMBL8797138 | 0.87 | HRH3 (0.34) | HRH3FFAR1PPARG | |
| SCHEMBL8797588 | 0.87 | DRD2 (0.36) | HRH3MAOBRAB9ANPC1 | |
| SCHEMBL8796899 | 0.87 | GAA (0.38) | HRH3MAOB | |
| SCHEMBL8797688 | 0.87 | HRH3 (0.35) | HRH3FFAR1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903343-B1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP CO LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0903343-A1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP Co., Ltd. (JP) | 1999-03-24 | — | — | EP | disclosed |
| EP-0787727-A1 | Benzoazine derivative or salt thereof and pharmaceutical composition comprising the same | SS Pharmaceutical Co., Ltd. (JP) | 1997-08-06 | — | — | EP | disclosed |