Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.33 |
| ▸ | PPARG | P37231 | 3/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | KDM4A | O75164 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8797318 | 0.90 | ESR1 (0.37) | ESR1ESR2 | |
| SCHEMBL8797111 | 0.89 | HRH3 (0.35) | HRH3FFAR1PPARGKDM4AUSP2 | |
| SCHEMBL8797027 | 0.89 | HRH3 (0.36) | HRH3FFAR1PPARGKDM4AUSP2 | |
| SCHEMBL8797688 | 0.88 | HRH3 (0.35) | HRH3FFAR1PPARGKDM4AUSP2 | |
| SCHEMBL8797588 | 0.88 | DRD2 (0.36) | HRH3ESR1ESR2MAOB | |
| SCHEMBL8797138 | 0.88 | HRH3 (0.34) | HRH3FFAR1PPARGESR1KDM4A | |
| SCHEMBL8797133 | 0.88 | HRH3 (0.34) | HRH3FFAR1PPARGKDM4AUSP2 | |
| SCHEMBL8797166 | 0.88 | BCHE (0.38) | HRH3 | |
| SCHEMBL8796797 | 0.88 | FFAR1 (0.39) | HRH3FFAR1PPARGMAOB | |
| SCHEMBL6953755 | 0.87 | HRH3 (0.40) | HRH3FFAR1PPARGMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787727-A1 | Benzoazine derivative or salt thereof and pharmaceutical composition comprising the same | SS Pharmaceutical Co., Ltd. (JP) | 1997-08-06 | — | — | EP | disclosed |