Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 4/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | ODC1 | P11926 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3294151 | 0.80 | DGAT1 (0.38) | DGAT1FDPSPDE3AODC1KDM4E | |
| SCHEMBL28328324 | 0.78 | ODC1 (0.37) | DGAT1ODC1KDM4ELMNAMAPT | |
| SCHEMBL11412905 | 0.77 | ODC1 (0.59) | DGAT1ODC1KDM4ELMNAMAPT | |
| SCHEMBL29874049 | 0.76 | DGAT1 (0.38) | DGAT1FDPSLMNABLMCYP1A2 | |
| SCHEMBL15319364 | 0.76 | DGAT1 (0.38) | DGAT1FDPSLMNABLMCYP1A2 | |
| SCHEMBL517552 | 0.76 | CYP4F2 (0.42) | DGAT1FDPSLMNABLMCYP1A2 | |
| SCHEMBL9016090 | 0.76 | ODC1 (0.42) | DGAT1ODC1KDM4ELMNAMAPT | |
| SCHEMBL2270879 | 0.76 | ODC1 (0.42) | DGAT1ODC1KDM4ELMNAMAPT | |
| SCHEMBL2270874 | 0.76 | ODC1 (0.42) | DGAT1ODC1KDM4ELMNAMAPT | |
| SCHEMBL31047206 | 0.75 | DGAT1 (0.45) | DGAT1FDPSPDE3ALMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0777660-A1 | NOVEL ALKYLAMINO DERIVATIVES AS SIGMA 2 SELECTIVE LIGANDS | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-06-11 | — | — | EP | disclosed |