Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMBR | P28336 | 11/20 | 0.70 |
| ▸ | TACR1 | P25103 | 1/20 | 0.61 |
| ▸ | MMP2 | P08253 | 3/20 | 0.60 |
| ▸ | MMP8 | P22894 | 3/20 | 0.60 |
| ▸ | MMP1 | P03956 | 2/20 | 0.60 |
| ▸ | TACR3 | P29371 | 1/20 | 0.58 |
| ▸ | MMP7 | P09237 | 1/20 | 0.58 |
| ▸ | MMP9 | P14780 | 1/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.56 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8797761 | 0.90 | NMBR (0.66) | NMBRTACR1MMP2MMP8MMP1 | |
| SCHEMBL6020210 | 0.86 | NMBR (0.66) | NMBRTACR1TACR3 | |
| SCHEMBL7439589 | 0.85 | CTSL (0.72) | NMBRTACR1TACR3 | |
| SCHEMBL6020516 | 0.85 | CTSL (0.72) | NMBRTACR1MMP2MMP8MMP1 | |
| SCHEMBL7443477 | 0.85 | CTSL (0.72) | NMBRTACR1TACR3 | |
| SCHEMBL6020039 | 0.85 | NMBR (0.66) | NMBRTACR1MMP2MMP8MMP1 | |
| SCHEMBL6020820 | 0.84 | CTSL (0.69) | NMBRTACR1MMP2MMP8MMP1 | |
| SCHEMBL8785114 | 0.83 | KCNA5 (0.63) | NMBR | |
| SCHEMBL3820631 | 0.83 | KCNA5 (0.63) | NMBR | |
| SCHEMBL4612012 | 0.83 | KCNA5 (0.63) | NMBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807114-A1 | BRIDGED INDOLES AS MATRIX METALLOPROTEASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1997-11-19 | — | — | EP | disclosed |