Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 17/20 | 0.80 |
| ▸ | AVPR1B | P47901 | 16/20 | 0.80 |
| ▸ | AVPR2 | P30518 | 13/20 | 0.60 |
| ▸ | OXTR | P30559 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8796741 | 0.88 | AVPR1A (0.73) | AVPR1AAVPR1BAVPR2 | |
| SCHEMBL8796709 | 0.84 | AVPR1A (0.70) | AVPR1AAVPR1BAVPR2 | |
| SCHEMBL6989046 | 0.83 | AVPR1A (1.00) | AVPR1AAVPR1BAVPR2OXTR | |
| SCHEMBL7346547 | 0.79 | AVPR1A (0.73) | AVPR1AAVPR1BAVPR2OXTR | |
| SCHEMBL7019432 | 0.79 | AVPR1A (0.65) | AVPR1AAVPR1BAVPR2 | |
| SCHEMBL8796584 | 0.79 | AVPR1A (0.61) | AVPR1AAVPR1BAVPR2 | |
| SCHEMBL8741346 | 0.79 | AVPR1A (0.81) | AVPR1AAVPR1BAVPR2 | |
| SCHEMBL8796878 | 0.79 | AVPR1A (0.67) | AVPR1AAVPR1BAVPR2OXTR | |
| SCHEMBL7014029 | 0.78 | AVPR1A (0.59) | AVPR1AAVPR1BAVPR2 | |
| SCHEMBL7020907 | 0.78 | AVPR1A (0.63) | AVPR1AAVPR1BAVPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811008-A1 | BICYCLIC BENZAZEPINE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | American Cyanamid Company (US) | 1997-12-10 | — | — | EP | disclosed |