Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 17/20 | 0.73 |
| ▸ | AVPR1B | P47901 | 15/20 | 0.73 |
| ▸ | AVPR2 | P30518 | 14/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8796584 | 0.90 | AVPR1A (0.61) | AVPR1AAVPR1BAVPR2 | |
| SCHEMBL8797250 | 0.88 | AVPR1A (0.80) | AVPR1AAVPR1BAVPR2 | |
| SCHEMBL8796709 | 0.82 | AVPR1A (0.70) | AVPR1AAVPR1BAVPR2 | |
| SCHEMBL7014029 | 0.77 | AVPR1A (0.59) | AVPR1AAVPR1BAVPR2 | |
| SCHEMBL6985550 | 0.77 | AVPR2 (0.47) | AVPR1AAVPR1BAVPR2KMT2A | |
| SCHEMBL7019432 | 0.77 | AVPR1A (0.65) | AVPR1AAVPR1BAVPR2 | |
| SCHEMBL8796878 | 0.76 | AVPR1A (0.67) | AVPR1AAVPR1BAVPR2 | |
| SCHEMBL7020907 | 0.76 | AVPR1A (0.63) | AVPR1AAVPR1BAVPR2LMNA | |
| SCHEMBL6989132 | 0.75 | AVPR1A (0.85) | AVPR1AAVPR1BAVPR2 | |
| SCHEMBL8741346 | 0.75 | AVPR1A (0.81) | AVPR1AAVPR1BAVPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811008-A1 | BICYCLIC BENZAZEPINE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | American Cyanamid Company (US) | 1997-12-10 | — | — | EP | disclosed |