Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 17/20 | 0.70 |
| ▸ | AVPR1B | P47901 | 14/20 | 0.70 |
| ▸ | AVPR2 | P30518 | 13/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8797250 | 0.84 | AVPR1A (0.80) | AVPR1AAVPR1BAVPR2 | |
| SCHEMBL6988983 | 0.84 | AVPR1A (0.79) | AVPR1AAVPR1BAVPR2 | |
| SCHEMBL8796741 | 0.82 | AVPR1A (0.73) | AVPR1AAVPR1BAVPR2 | |
| SCHEMBL7019432 | 0.80 | AVPR1A (0.65) | AVPR1AAVPR1BAVPR2 | |
| SCHEMBL8796707 | 0.79 | AVPR1A (0.74) | AVPR1AAVPR1BAVPR2 | |
| SCHEMBL7344114 | 0.79 | AVPR1A (0.58) | AVPR1AAVPR1BAVPR2 | |
| SCHEMBL7020907 | 0.79 | AVPR1A (0.63) | AVPR1AAVPR1BAVPR2 | |
| SCHEMBL6989537 | 0.77 | AVPR1A (0.55) | AVPR1AAVPR1BAVPR2 | |
| SCHEMBL6993669 | 0.77 | AVPR1A (0.79) | AVPR1AAVPR1BAVPR2 | |
| SCHEMBL8796903 | 0.76 | AVPR1A (0.74) | AVPR1AAVPR1BAVPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811008-A1 | BICYCLIC BENZAZEPINE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | American Cyanamid Company (US) | 1997-12-10 | — | — | EP | disclosed |